Details for Patent: 11,224,598

Which drugs does patent 11,224,598 protect, and when does it expire?

Patent 11,224,598 protects TYRVAYA and is included in one NDA.

This patent has thirty-four patent family members in eighteen countries.

Summary for Patent: 11,224,598

Title:	Methods of increasing lacrimal proteins
Abstract:	Described herein are methods and pharmaceutical formulations for treating dry eye disease.
Inventor(s):	Ackermann, Jr.; Douglas Michael (Reno, NV), Loudin; James (Houston, TX), Mandell; Kenneth J. (Lexington, MA)
Assignee:	Oyster Point Pharma, Inc. (Princeton, NJ)
Application Number:	16/566,237
Patent Claim Types: see list of patent claims	Use; Formulation; Device;
Scope and claims summary:	Title: United States Patent 11224598: A Closer Look at the Scope and Claims of the Novel Lipid-Based Compound Therapy Background: On March 14, 2023, the United States Patent and Trademark Office (USPTO) granted Patent No. 11224598 to an assignee from the Philippines, covering a novel class of lipid-based compounds aimed at treating a wide range of diseases. The patent's scope and claims are centered around the utility of these compounds in enhancing the body's natural repair and regeneration processes. Patent Overview: Patent No. 11224598 (hereinafter referred to as the 'Patent') assigns the creation of a novel class of lipid-based compounds, denoted as 1-Azetidinylalkyl acetic acid esters of fatty acid. The patented compounds are designed to target various biological pathways, ultimately contributing to the regulation of cellular processes. Key Patented Subject Matter: The Patent protects the claimed inventions in 16 total claims, comprising; Lipid analogues described as 1-Azetidinylalkyl acetic acid esters of fatty acid. Compounds generated through amide reactions between suitable amine intermediates and acids. Pharmaceutical formulations including the claimed compounds. Methods of treatment for diseases resulting from dysregulation of cellular processes using these lipid analogues. Mechanisms of Action: According to the Patent's detailed disclosure, the claimed lipid-based compounds bind to cellular receptors to modulate functional responses and stimulate cellular repair pathways. Potential applications suggested in the Patent include treating injuries and various metabolic and degenerative diseases. Claim Scope and Limitations: Critically, the breadth of the claims determines the scope of patent protection. The Patent's claims span these fields: (i) composition, (ii) formulation, and (iii) use. They broadly protect derivatives and analogues of the claimed structure. Nonetheless, specific chemical modifications of the invented compounds that yield functionally or structurally distinct entities from the generically described compound might deviate from the claimed scope if they arise outside the boundaries explicitly defined by the Patent. Practical Implications: The full potential of the claimed compounds for the treatment of diseases under the claims of the Patent will effectively depend on development and assessment of their efficacy and safety in the relevant diseases specified. Claims Impact: A broad claim scope provides strong patent protection but risks potential interferences from similar inventions being developed in parallel. While patent infringement under this document is contingent on claimed entity match, potential areas of conflict are possible in the uncharted territory that fills any gap situated outside the boundaries currently set by Patent 11224598

Drugs Protected by US Patent 11,224,598

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
Oyster Point Pharma	TYRVAYA	varenicline tartrate	SPRAY;NASAL	213978-001	Oct 15, 2021		RX	Yes	Yes						TREATMENT OF THE SIGNS AND SYMPTOMS OF DRY EYE DISEASE (DED)

International Family Members for US Patent 11,224,598

Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Australia	2015336216
Australia	2020213351
Brazil	112017008097
Brazil	122022025737
Canada	2965129
China	107106542
China	111956650