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Last Updated: October 31, 2024

Details for Patent: 11,446,380


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Which drugs does patent 11,446,380 protect, and when does it expire?

Patent 11,446,380 protects OXLUMO and is included in one NDA.

This patent has sixty-one patent family members in forty countries.

Summary for Patent: 11,446,380
Title:Compositions and methods for inhibition of HAO1 (hydroxyacid oxidase 1 (glycolate oxidase)) gene expression
Abstract: The invention relates to RNAi agents, e.g., double-stranded RNAi agents, targeting the HAO1 gene, and methods of using such RNAi agents to inhibit expression of HAO1 and methods of treating subjects having, e.g., PH1.
Inventor(s): Querbes; William (Boston, MA), Fitzgerald; Kevin (Brookline, MA), Bettencourt; Brian (Groton, MA), Liebow; Abigail (Somerville, MA), Erbe; David V. (Arlington, MA)
Assignee: Alnylam Pharmaceuticals, Inc. (Cambridge, MA)
Application Number:16/673,863
Patent Claim Types:
see list of patent claims
Composition; Formulation; Compound;

Drugs Protected by US Patent 11,446,380

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Alnylam Pharms Inc OXLUMO lumasiran sodium SOLUTION;SUBCUTANEOUS 214103-001 Nov 23, 2020 RX Yes Yes ⤷  Sign Up ⤷  Sign Up Y Y ⤷  Sign Up
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 11,446,380

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 3204015 ⤷  Sign Up 301167 Netherlands ⤷  Sign Up
European Patent Office 3204015 ⤷  Sign Up PA2022004 Lithuania ⤷  Sign Up
European Patent Office 3204015 ⤷  Sign Up CA 2022 00011 Denmark ⤷  Sign Up
European Patent Office 3204015 ⤷  Sign Up 2022C/509 Belgium ⤷  Sign Up
European Patent Office 3204015 ⤷  Sign Up LUC00252 Luxembourg ⤷  Sign Up
European Patent Office 3204015 ⤷  Sign Up 122022000018 Germany ⤷  Sign Up
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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