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Last Updated: April 8, 2025

Details for Patent: 3,632,645


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Summary for Patent: 3,632,645
Title:Substituted phenylacetyl derivatives of guanidine o-alkylisoureas s-alkylisothioureas and p-nitrobenzylisothiourea
Abstract:THE INVENTION PROVIDES ACETYL-GUANIDINE DERIVATIVES OF FORMULA:IN WHICH R1 IS A CHLORINE ATOMS, OR METHYL RADICAL. THE ACETYL-GUANIDINE DERIVATIVES ARE USEFUL AS ANTIHYPERTENSIVES. 1,3-DI(R-),2-(H2N-C(-NH2)=N-CO-CH2-)BENZENE 1,3-DI(R1-),2-(HN=C(-NH2)-NH-CO-CH2-)BENZENE AND
Inventor(s):John Bernard Bream, Claude W Picard
Assignee:Wander AG, Novartis Pharmaceuticals Corp
Application Number:US761806A
Patent Claim Types:
see list of patent claims
Patent landscape, scope, and claims:

United States Patent 3,632,645: A Detailed Analysis of Scope and Claims

Overview of the Patent

United States Patent 3,632,645, titled "Substituted phenylacetyl derivatives of guanidine," was granted on January 4, 1972. This patent is associated with the invention of specific acetyl-guanidine derivatives, which are described in detail within the patent documentation.

Inventors and Assignees

The patent was filed by the inventors who developed these specific chemical compounds, although the specific names of the inventors are not provided in the publicly available summary. The assignee of the patent is not explicitly mentioned in the sources, but it is typical for such patents to be assigned to the company or institution that sponsored the research.

Claims of the Patent

Independent Claims

The patent includes several claims that define the scope of the invention. Here are the key aspects of the claims:

  • Chemical Structure: The patent claims involve acetyl-guanidine derivatives with specific substitutions. For example, the formula includes R1 being a chlorine atom or a methyl radical[4].
  • Synthesis and Composition: The claims detail the methods of synthesizing these compounds and their chemical compositions.

Dependent Claims

Dependent claims further specify the invention by detailing various aspects such as:

  • Specific Substitutions: Different substituents on the phenyl ring and the guanidine moiety.
  • Pharmaceutical Applications: Potential uses of these compounds, although this is not explicitly stated in the sources provided.

Scope of the Patent

Chemical Scope

The scope of the patent is limited to the specific acetyl-guanidine derivatives described. This includes variations in the substituents on the phenyl ring and the guanidine part of the molecule. The patent does not cover broader classes of compounds but is narrowly focused on these specific derivatives[4].

Pharmaceutical Scope

While the patent does not explicitly mention pharmaceutical applications, compounds of this nature are often investigated for their potential therapeutic uses. The scope in this context would be limited to any medical or biological applications that these specific compounds might have.

Patent Landscape

Prior Art

The patent cites several prior art references related to guanidine compounds and their derivatives. These references are crucial in establishing the novelty and non-obviousness of the invention[4].

Related Patents

Other patents related to guanidine derivatives and similar chemical compounds can be found in various jurisdictions. For instance, patents like US3632645A have counterparts in other countries such as AT293421B, BE721328A, and others, indicating a global interest in these chemical compounds[4].

Expiration and Current Status

The patent has expired, as indicated by its legal status. The expiration date would have been 17 years from the grant date or earlier if the patent term was adjusted due to regulatory reviews or other factors[2][4].

Impact on Innovation and Patent Quality

Patent Quality Metrics

The quality of this patent can be evaluated using metrics such as independent claim length and independent claim count, as discussed in the Hoover Institution paper. Narrower claims, like those in this patent, are often associated with a higher probability of grant and shorter examination processes[3].

Litigation and Licensing

The specificity of the claims in this patent reduces the likelihood of litigation and licensing issues that are common with broader or unclear claims. This specificity helps in maintaining clarity and validity, which are crucial for innovation[3].

Key Takeaways

  • Specificity of Claims: The patent is narrowly focused on specific acetyl-guanidine derivatives.
  • Chemical Scope: The scope is limited to the described chemical structures and their synthesis.
  • Pharmaceutical Potential: While not explicitly stated, these compounds could have potential therapeutic applications.
  • Patent Status: The patent has expired.
  • Impact on Innovation: The specificity of the claims contributes to higher patent quality and reduced litigation risks.

FAQs

Q: What are the main compounds described in US Patent 3,632,645?

A: The patent describes acetyl-guanidine derivatives with specific substitutions, including chlorine atoms or methyl radicals.

Q: What is the current status of US Patent 3,632,645?

A: The patent has expired.

Q: How does the specificity of claims in this patent impact innovation?

A: The specificity reduces the likelihood of litigation and licensing issues, contributing to higher patent quality and clearer boundaries for innovation.

Q: Are there related patents in other jurisdictions?

A: Yes, there are related patents in various countries such as Austria, Belgium, and others.

Q: What metrics can be used to evaluate the quality of this patent?

A: Metrics such as independent claim length and independent claim count can be used to evaluate the quality of this patent.

Sources

  1. US Patent and Trademark Office: US3632645A - Substituted phenylacetyl derivatives of guanidine.
  2. United States Patent and Trademark Office: Extension Under 35 U.S.C. 156(e)(1).
  3. Hoover Institution: Patent Claims and Patent Scope.
  4. Google Patents: US3632645A - Substituted phenylacetyl derivatives of guanidine.

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Drugs Protected by US Patent 3,632,645

ApplicantTradenameGeneric NameDosageNDAApproval DateTETypeRLDRSPatent No.Patent ExpirationProductSubstanceDelist Req.Patented / Exclusive UseSubmissiondate
No data available in table
>Applicant>Tradename>Generic Name>Dosage>NDA>Approval Date>TE>Type>RLD>RS>Patent No.>Patent Expiration>Product>Substance>Delist Req.>Patented / Exclusive Use>Submissiondate
Showing 0 to 0 of 0 entries

International Family Members for US Patent 3,632,645

CountryPatent NumberEstimated ExpirationSupplementary Protection CertificateSPC CountrySPC Expiration
Austria 293421 ⤷  Try for Free
Belgium 721328 ⤷  Try for Free
Brazil 6802577 ⤷  Try for Free
Canada 959860 ⤷  Try for Free
Cyprus 759 ⤷  Try for Free
Czechoslovakia 158625 ⤷  Try for Free
Switzerland 479559 ⤷  Try for Free
>Country>Patent Number>Estimated Expiration>Supplementary Protection Certificate>SPC Country>SPC Expiration
Showing 1 to 7 of 7 entries

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Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.