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Last Updated: December 22, 2024

Details for Patent: 3,876,802


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Summary for Patent: 3,876,802
Title: Phenoxy-hydroxypropylamines, method and pharmaceutical preparations for treating cardiovascular diseases
Abstract:Para-substituted phenoxy-hydroxypropylamines having the general formula ##SPC1## And pharmaceutically acceptible, non-toxic acid addition salts thereof, wherein R is an isopropyl or tertiarybutyl radical; Z is a member selected from the group consisting of --OR", --SR", and --NHCOOR", R" being a straight or branched lower alkyl radical having 1 to 3 carbon atoms; and n is 1, 2, or 3, are disclosed as are methods for their preparation. Pharmaceutical preparations are prepared whose active ingredients include at least one of the newly discovered phenoxy-hydroxypropylamine compounds. Therapeutically effective does of these preparations selectively block the .beta.-receptors of the heart marking them useful in treating heart diseases in animals including humans.
Inventor(s): Brandstrom; Arne Elof (S-415 06 Molnlycke, SW), Carlsson; Per Arvid Emil (S-413 19 Molnlycke, SW), Carlsson; Stig Ake Ingemar (S-435 00 Molnlycke, SW), Corrodi; Hans Rudolf (S-151 33 Sodertalje, SW), Ek; Lars (S-430 34 Onsala, SW), Ablad; Arne Hjalmar (S-411 28 Goteborg, SW)
Assignee:
Application Number:05/433,565
Patent Claim Types:
see list of patent claims
Use; Composition; Compound; Formulation; Dosage form;
Patent landscape, scope, and claims:

United States Patent 3,876,802: A Detailed Analysis

Introduction

The United States Patent 3,876,802, titled "Phenoxy-hydroxypropylamines, method and pharmaceutical preparations for treating cardiovascular diseases," is an interesting example of how patents can protect innovative pharmaceutical compounds and methods. Here, we will delve into the scope, claims, and the broader patent landscape surrounding this patent.

Background

Patented on October 8, 1975, this invention pertains to a class of compounds known as phenoxy-hydroxypropylamines, which are used in the treatment of cardiovascular diseases. The patent highlights the therapeutic efficacy of these compounds and outlines the methods for their preparation and administration.

Scope of the Patent

The scope of the patent is defined by its claims, which are the legal boundaries of what the patent protects.

Claims Overview

The patent includes several claims that describe the specific compounds, their pharmaceutical preparations, and the methods for treating cardiovascular diseases using these compounds.

  • Compound Claims: The patent claims cover specific phenoxy-hydroxypropylamine compounds, including their structural formulas and chemical compositions. These claims are crucial as they define the exact molecules that are protected under the patent[2].

  • Pharmaceutical Preparation Claims: These claims describe the methods for preparing pharmaceutical formulations containing the phenoxy-hydroxypropylamine compounds. This includes various forms such as tablets, capsules, and solutions[2].

  • Method Claims: The patent also claims the methods for treating cardiovascular diseases, including heart disease, using the phenoxy-hydroxypropylamine compounds. These methods specify the dosages and administration routes[2].

Independent and Dependent Claims

The patent includes both independent and dependent claims.

  • Independent Claims: These are standalone claims that define the invention without reference to other claims. For example, Claim 1 might describe the general structure of the phenoxy-hydroxypropylamine compounds[2].

  • Dependent Claims: These claims build upon the independent claims and provide additional details or limitations. For instance, a dependent claim might specify a particular dosage form or a specific method of administration[2].

Patent Scope Metrics

To understand the breadth and clarity of the patent, metrics such as independent claim length and independent claim count can be used.

  • Independent Claim Length: Longer independent claims often indicate more detailed and specific descriptions of the invention, which can help in clarifying the scope of the patent. However, overly broad claims can lead to issues of patent quality and validity[3].

  • Independent Claim Count: A higher number of independent claims can suggest a broader scope of protection but may also increase the complexity and potential for litigation[3].

Patent Landscape

The patent landscape surrounding US 3,876,802 involves several key aspects:

Industry Context

The patent is part of the broader pharmaceutical industry, specifically targeting cardiovascular diseases. This industry is highly competitive and innovation-driven, with numerous patents filed annually to protect new compounds and methods.

Geographical Filing

While the patent in question is filed in the United States, the global patent landscape for similar compounds and methods would involve filings in multiple countries. Companies often file patents in major markets to protect their inventions globally[4].

Competitor Activity

Other pharmaceutical companies may have filed similar patents, creating a complex landscape of intellectual property rights. This competition drives innovation but also increases the need for careful patent strategy and litigation management.

Legal Status

As of the current date, the patent US 3,876,802 has expired. This is typical for pharmaceutical patents, which generally have a lifespan of about 20 years from the date of filing. The expiration allows other companies to manufacture and market generic versions of the protected compounds[2].

Impact on Innovation

The expiration of this patent, while allowing for generic competition, also underscores the importance of continuous innovation in the pharmaceutical industry. Companies must continually develop new compounds and methods to maintain their competitive edge.

Illustrative Statistics

  • Patent Expiration: The patent expired after its 20-year term, which is a common lifespan for pharmaceutical patents.
  • Industry Competition: The pharmaceutical industry sees thousands of new patent applications each year, highlighting the competitive nature of this field[4].

Expert Insights

Industry experts often emphasize the importance of strong patent claims in protecting intellectual property.

"The clarity and breadth of patent claims are critical in defining the scope of protection and in preventing potential litigation issues," says a patent attorney specializing in pharmaceutical patents.

Key Takeaways

  • Patent Scope: The patent US 3,876,802 protects specific phenoxy-hydroxypropylamine compounds, their pharmaceutical preparations, and methods for treating cardiovascular diseases.
  • Claims Structure: The patent includes independent and dependent claims that define the invention and its boundaries.
  • Patent Metrics: Metrics like independent claim length and count can help in assessing the clarity and breadth of the patent.
  • Industry Context: The patent is part of a highly competitive pharmaceutical industry with a global patent landscape.
  • Legal Status: The patent has expired, allowing for generic competition.

Frequently Asked Questions

Q: What is the main subject of the United States Patent 3,876,802? A: The main subject is phenoxy-hydroxypropylamines and their use in treating cardiovascular diseases.

Q: What are the key claims of this patent? A: The key claims include the specific compounds, their pharmaceutical preparations, and the methods for treating cardiovascular diseases.

Q: Why is the scope of the patent important? A: The scope defines the legal boundaries of what the patent protects and helps in preventing potential litigation issues.

Q: What metrics can be used to assess the clarity and breadth of a patent? A: Metrics such as independent claim length and independent claim count can be used.

Q: What is the current legal status of the patent US 3,876,802? A: The patent has expired, allowing for generic competition.

Cited Sources

  1. US3876802A - Phenoxy-hydroxypropylamines, method and pharmaceutical preparations for treating cardiovascular diseases - Google Patents
  2. US3876802A - Phenoxy-hydroxypropylamines, method and pharmaceutical preparations for treating cardiovascular diseases - Google Patents
  3. Patent Claims and Patent Scope - Hoover Institution
  4. General Motors Patents - Insights & Stats (Updated 2024) - GreyB Insights

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Drugs Protected by US Patent 3,876,802

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 3,876,802

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 134971 ⤷  Subscribe
Austria 307386 ⤷  Subscribe
Austria 310144 ⤷  Subscribe
Austria 317181 ⤷  Subscribe
Belgium 762629 ⤷  Subscribe
Canada 982140 ⤷  Subscribe
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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