Details for Patent: 4,124,707
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Summary for Patent: 4,124,707
Title: | 7.alpha.-Halogeno-3,20-dioxo-1,4-pregnadienes, methods for their manufacture, their use as anti-inflammatory agents, and pharmaceutical formulations useful therefor |
Abstract: | Novel 3,20-dioxo-7.alpha.-halogeno-1,4-pregnadienes are described and their use as anti-inflammatory agents. Preferred are 7.alpha.-bromo- and 7.alpha.-chloro- derivatives, particularly 7.alpha.-bromo- and 7.alpha.-chloro-1,4-pregnadienes-11.beta.,17.alpha.,21-triol-3,20-dione 17,21-dihydrocarboncarboxylates, the 16-methyl and 16-methylene derivatives thereof being particularly valuable as topical anti-inflammatory agents. |
Inventor(s): | Green; Michael J. (Kendall Park, NJ), Shue; Ho-Jane (Belleville, NJ) |
Assignee: | Schering Corporation (Kenilworth, NJ) |
Application Number: | 05/848,856 |
Patent Claim Types: see list of patent claims | Compound; Use; Composition; |
Drugs Protected by US Patent 4,124,707
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