Details for Patent: 4,444,784

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Summary for Patent: 4,444,784

Title:	Antihypercholesterolemic compounds
Abstract:	6(R)-[2-(8'-acyloxy-2'-methyl-6'-methyl (or hydrogen)-polyhydronaphthyl-1')-ethyl]-4 (R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-ones are prepared by acylation of the corresponding 8'-hydroxy compounds. The products are strong inhibitors of the biosynthesis of cholesterol.
Inventor(s):	Hoffman; William F. (Lansdale, PA), Smith; Robert L. (Lansdale, PA), Willard; Alvin K. (DE)
Assignee:	Merck & Co., Inc. (Rahway, NJ)
Application Number:	06/217,640
Patent Claim Types: see list of patent claims	Compound; Composition; Use;

Drugs Protected by US Patent 4,444,784

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