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Last Updated: November 4, 2024

Details for Patent: 4,447,424


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Summary for Patent: 4,447,424
Title: Steroid derivatives
Abstract:Novel 19-nor steroids and 19-nor-D-homo-steroids of the formula ##STR1## wherein R.sub.1 is an organic radical of 1 to 18 carbon atoms containing at least one atom selected from the group consisting of nitrogen, phosphorous and silicon with the atom immediately adjacent to the 11-carbon atom being carbon, R.sub.2 is a hydrocarbon of 1 to 8 carbon atoms, X is selected from the group consisting of a pentagonal ring and a hexagonal ring optionally substituted and optionally containing a double bond, B and C together form a double bond or an epoxy group, the C.dbd.A group at position 3 is selected from the group consisting of C--O, ketal, which may be open or closed ##STR2## --C.dbd.NOH, --C--NOAlK.sub.3 and C--CH.sub.2, AlK.sub.1, AlK.sub.2 and AlK.sub.3 are selected from the group consisting of alkyl of 1 to 8 carbon atoms and aralkyl of 7 to 15 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts having anti-glucocorticoid activity and a process for their preparation.
Inventor(s): Teutsch; Jean G. (Pantin, FR), Costerousse; Germain (Saint-Maurice, FR), Philibert; Daniel (La Varenne Saint Hilaire, FR), Deraedt; Roger (Pavillons sous Bois, FR)
Assignee: Roussel Uclaf (Paris, FR)
Application Number:06/386,967
Patent Claim Types:
see list of patent claims
Composition; Compound; Use; Delivery;

Drugs Protected by US Patent 4,447,424

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 4,447,424

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
France81 00272Jan 09, 1981

International Family Members for US Patent 4,447,424

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 0057115 ⤷  Sign Up SPC/GB93/030 United Kingdom ⤷  Sign Up
Austria 12239 ⤷  Sign Up
Austria 23167 ⤷  Sign Up
Austria 23344 ⤷  Sign Up
Austria 396787 ⤷  Sign Up
Austria 46702 ⤷  Sign Up
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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