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Last Updated: December 23, 2024

Details for Patent: 4,452,774


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Summary for Patent: 4,452,774
Title: Isonitrile radionuclide complexes for labelling and imaging agents
Abstract:A coordination complex of an isonitrile ligand and radionuclide such as Tc, Ru, Co, Pt, Fe, Os, Ir, W, Re, Cr, Mo, Mn, Ni, Rh, Pd, Nb and Ta, is useful as a diagnostic agent for labelling liposomes or vesicles, and selected living cells containing lipid membranes, such as blood clots, myocardial tissue, gall bladder tissue, etc.
Inventor(s): Jones; Alun G. (Newton Centre, MA), Davison; Alan (Needham, MA), Abrams; Michael J. (Allston, MA)
Assignee: President and Fellows of Harvard College (Cambridge, MA) Massachusetts Institute of Technology (Cambridge, MA)
Application Number:06/373,511
Patent Claim Types:
see list of patent claims
Compound; Device; Use; Composition; Dosage form;
Patent landscape, scope, and claims:

Analyzing the Scope and Claims of United States Patent 4,452,774: A Comprehensive Guide

Introduction

Understanding the scope and claims of a patent is crucial for inventors, researchers, and businesses to navigate the complex landscape of intellectual property. This article will delve into the details of United States Patent 4,452,774, titled "Isonitrile radionuclide complexes for labelling and imaging," and provide a comprehensive analysis of its scope and claims.

Background of the Patent

United States Patent 4,452,774, issued on June 5, 1984, pertains to novel isonitrile complexes of radionuclides. These complexes are designed for labeling and imaging purposes, particularly in medical diagnostics. The patent describes the synthesis and application of these complexes, which involve radioactive isotopes such as Technetium-99m (.sup.99m Tc)[5].

Understanding Patent Claims

Patent claims are the heart of any patent application, defining the scope of protection granted to the inventor. Here’s how to analyze the claims of US Patent 4,452,774:

Claim Structure

The claims in a patent are typically divided into independent and dependent claims. Independent claims stand alone and define the broadest scope of the invention, while dependent claims refer back to and further limit the independent claims.

Claim Analysis of US Patent 4,452,774

  • Independent Claims: These claims outline the core invention, including the composition of the isonitrile radionuclide complexes and their method of preparation.
    • For example, Claim 1 might describe the general structure of the isonitrile complex, including the radionuclide and the ligand.
  • Dependent Claims: These claims narrow down the scope by specifying particular aspects of the invention, such as specific radionuclides, ligands, or methods of use.
    • Dependent claims might include variations of the complex, such as different isotopes or additional components that enhance stability or efficacy.

Scope of the Patent

The scope of a patent is defined by its claims and is critical for determining what is protected and what is not.

Technical Scope

  • The patent covers the synthesis and use of isonitrile complexes with radionuclides, particularly for medical imaging.
  • It includes specific chemical structures and methods for preparing these complexes.
  • The scope extends to various applications, such as diagnostic imaging using .sup.99m Tc.

Legal Scope

  • The legal scope is defined by the jurisdiction in which the patent is granted. For US Patent 4,452,774, this means the protection is limited to the United States.
  • The patent’s legal scope also includes any subsequent patents or continuations that may have been filed, which could broaden or narrow the original claims.

Patent Landscape Analysis

Analyzing the patent landscape involves understanding the broader context of related patents and how they interact with the patent in question.

Related Patents

  • Other patents related to radionuclide complexes and medical imaging can provide insight into the competitive landscape.
  • Tools like the USPTO’s Patent Public Search or international databases such as the European Patent Office’s esp@cenet can be used to find similar patents[1].

Global Dossier

  • Using the Global Dossier service, one can view the patent family for US Patent 4,452,774, including related applications filed in other countries. This helps in understanding the global protection and any variations in claims across different jurisdictions[1].

Patent Analytics and Claim Coverage

Patent analytics can help in understanding the coverage and gaps in the patent portfolio.

Claim Coverage Matrix

  • A Claim Coverage Matrix can be used to categorize patents by claims and scope concepts. This helps in identifying which patents and claims are actively protecting the intellectual property related to isonitrile radionuclide complexes[4].

Claim Charts

  • Interactive claim charts generated by tools like ClaimScape® can help technical experts review patent coverage. These charts can highlight gaps in current coverage and future design opportunities[4].

Practical Applications and Impact

Understanding the scope and claims of US Patent 4,452,774 has practical implications for research, development, and commercialization.

Medical Imaging

  • The patent’s focus on isonitrile radionuclide complexes for medical imaging means that any new developments in this area must consider the existing claims to avoid infringement.
  • Researchers and companies can use this patent as a foundation to develop new diagnostic tools, ensuring they stay within the bounds of what is not already protected.

Licensing and Collaboration

  • Companies may need to license the technology described in the patent or collaborate with the patent holders to develop new products.
  • Understanding the scope of the patent helps in negotiating licensing agreements and ensuring compliance with intellectual property laws.

Challenges and Limitations

Analyzing the scope and claims of a patent also involves understanding its limitations.

Expiration and Maintenance

  • Patents have a limited lifespan, typically 20 years from the filing date. US Patent 4,452,774 has already expired, meaning the technology it describes is now in the public domain.
  • Maintenance fees are no longer applicable, but understanding the historical context of the patent can still be valuable for current research and development.

International Protection

  • While the patent itself is limited to the United States, similar patents may have been filed in other countries. This requires a global search to understand the full scope of protection[1].

Key Takeaways

  • Patent Claims: The claims define the scope of protection and are crucial for understanding what is protected.
  • Scope Analysis: The technical and legal scope of the patent must be analyzed to determine its applicability and limitations.
  • Patent Landscape: Understanding related patents and the global dossier helps in navigating the competitive landscape.
  • Patent Analytics: Tools like Claim Coverage Matrix and Claim Charts are essential for managing and analyzing patent portfolios.
  • Practical Applications: The patent’s practical applications, especially in medical imaging, must be considered in light of its claims and scope.

FAQs

Q: What is the main subject of US Patent 4,452,774?

A: The main subject is the synthesis and use of isonitrile radionuclide complexes, particularly for medical imaging.

Q: How do I analyze the claims of a patent?

A: Analyze the independent and dependent claims to understand the core invention and its variations. Use tools like Claim Coverage Matrix and Claim Charts to categorize and visualize the claims.

Q: Is US Patent 4,452,774 still in force?

A: No, the patent has expired, and the technology it describes is now in the public domain.

Q: How can I find related patents globally?

A: Use databases like the USPTO’s Patent Public Search, the European Patent Office’s esp@cenet, or the Global Dossier service to find related patents and understand the global patent landscape.

Q: What is the significance of patent analytics in managing a patent portfolio?

A: Patent analytics helps in identifying gaps and opportunities in the patent portfolio, ensuring that the intellectual property is adequately protected and that future design options are explored.

Sources

  1. USPTO - Search for patents. Retrieved from https://www.uspto.gov/patents/search
  2. USPTO - Patent Claims Research Dataset. Retrieved from https://www.uspto.gov/ip-policy/economic-research/research-datasets/patent-claims-research-dataset
  3. U.S. Department of Commerce - U.S. Patent and Trademark Office. Retrieved from https://www.commerce.gov/bureaus-and-offices/uspto
  4. Schwegman Lundberg & Woessner - Patent Analytics. Retrieved from https://www.slwip.com/services/patent-analytics/
  5. Justia - US Patent for Isonitrile radionuclide complexes for labelling and imaging. Retrieved from https://patents.justia.com/patent/4452774

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Drugs Protected by US Patent 4,452,774

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 4,452,774

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 0107734 ⤷  Subscribe SPC/GB93/166 United Kingdom ⤷  Subscribe
European Patent Office 0107734 ⤷  Subscribe 93C0042 Belgium ⤷  Subscribe
Austria 28568 ⤷  Subscribe
Canada 1218666 ⤷  Subscribe
Germany 3372709 ⤷  Subscribe
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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