Details for Patent: 4,913,906
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Summary for Patent: 4,913,906
Title: | Novel controlled release dosage form of valproic acid |
Abstract: | The invention relates to controlled release pharmaceutical compositions. These contain as active ingredient valproic acid, a salt of valproic acid, an ester of valproic acid, Valpromide, or any other pharmaceutically acceptable derivative of valproic acid which upon administration to humans provides a serum level of valproic acid, in combination with an additive which is selected from physiologically acceptable polymeric substances and from native proteins. The active ingredient is usually in the range of from 10 to 80 weight percent. The novel pharmaceutical compositions are prepared by applying a high pressure to a mixture of the ingredients. They result in a prolonged serum level of the active ingredient. |
Inventor(s): | Friedman; Michael (Jerusalem, IL), Bialer; Meir (Jerusalem, IL), Rubinstein; Avraham (Jerusalem, IL), Dufrovsky; Upd (Tel-Aviv, IL) |
Assignee: | |
Application Number: | 06/832,244 |
Patent Claim Types: see list of patent claims | Compound; Dosage form; Process; | More… ↓ |
Drugs Protected by US Patent 4,913,906
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
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>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
Foreign Priority and PCT Information for Patent: 4,913,906
Foriegn Application Priority Data | ||
Foreign Country | Foreign Patent Number | Foreign Patent Date |
Israel | 74468 | Feb 28, 1985 |
International Family Members for US Patent 4,913,906
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
---|---|---|---|---|---|
Canada | 2009890 | ⤷ Subscribe | |||
European Patent Office | 0442012 | ⤷ Subscribe | |||
Israel | 74468 | ⤷ Subscribe | |||
>Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |