Details for Patent: 5,126,375

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Summary for Patent: 5,126,375

Title:	Phenethanolamine derivatives
Abstract:	Phenethanolamine derivatives are disclosed of formula ##STR1## wherein m is 2 to 8; n is 1 to 7 provided that m+n is 4 to 12; Ar is phenyl or phenyl substituted by one or two halogen atoms, alkyl or alkoxy groups or by an alkylenedioxy group; R.sup.1 and R.sup.2 are hydrogen or alkyl provided that the sum total of carbon atoms in R.sup.1 and R.sup.2 is not more than 4; and the physiologically acceptable salts and solvates thereof. The compounds have a selective stimulant action at .beta..sub.2 -adrenoreceptors and may be used inter alia in the treatment of diseases associated with reversible airways obstructions such as asthma and chronic bronchitis. The compounds may be formulated in conventional manner as pharmaceutical compositions with physiologically acceptable carriers or excipients. The compounds may be prepared, for example by alkylation of an amine: ##STR2## where R.sup.3, R.sup.5 and R.sup.6 is hydrogen or a protecting group, followed by removal of any protecting group.
Inventor(s):	Skidmore; Ian F. (Herts, GB2), Lunts; Lawrence H. C. (Herts, GB2), Finch; Harry (Herts, GB2), Naylor; Alan (Herts, GB2)
Assignee:	Glaxo Group Ltd. (London, GB)
Application Number:	07/619,899
Patent Claim Types: see list of patent claims	Compound; Composition;

Drugs Protected by US Patent 5,126,375

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

Foreign Priority and PCT Information for Patent: 5,126,375

Foriegn Application Priority Data
Foreign Country	Foreign Patent Number	Foreign Patent Date
Japan	8310477	Apr 18, 1983
Japan	8317087	Jun 23, 1983
Japan	8329568	Nov 04, 1983
Japan	8401889	Jan 25, 1984

International Family Members for US Patent 5,126,375

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Australia	2706484	⤷ Sign Up
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