Details for Patent: 5,308,847

Summary for Patent: 5,308,847

Title:	Methods of inhibiting transplant rejection in mammals using rapamycin and derivatives and prodrugs thereof
Abstract:	This invention provides a method of inhibiting organ or tissue transplant rejection in a mammal in need thereof, comprising administering to said mammal a transplant rejection inhibiting amount of rapamycin. Also disclosed is a method of inhibiting organ or tissue transplant rejection in a mammal in need thereof, comprising administering to said mammal (a) an amount of rapamycin in combination with (b) an amount of one or more other chemotherapeutic agents for inhibiting transplant rejection, e.g., azathioprine, corticosteroids, cyclosporin and FK506, said amounts of (a) and (b) together being effective to inhibit transplant rejection and to maintain inhibition of transplant rejection.
Inventor(s):	Calne; Sir Roy (Cambridge, GB2)
Assignee:
Application Number:	08/009,570
Patent Claim Types: see list of patent claims	Use; Delivery;

Drugs Protected by US Patent 5,308,847

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate

International Family Members for US Patent 5,308,847

Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
European Patent Office	0401747		CA 2001 00025	Denmark
European Patent Office	0401747		SPC/GB01/036	United Kingdom
European Patent Office	0401747		25/2001	Austria
Austria	135215