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Last Updated: March 24, 2025

Details for Patent: 5,317,016


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Summary for Patent: 5,317,016
Title: Pyrrolidylthiocarbapenem derivative
Abstract:A pyrrolidylthiocarbapenem derivative represented by Formula I is provided: ##STR1## wherein R.sup.1 is hydrogen or lower alkyl; R.sup.2, R.sup.3 and R.sup.4 are hydrogen, lower alkyl which can be substituted or an amino protecting group independently, or R.sup.2 and R.sup.3 together with a nitrogen atom to which R.sup.2 and R.sup.3 are bonded form a saturated or unsaturated cyclic group, or R.sup.2 and R.sup.4, or R.sup.3 and R.sup.4 together with two nitrogen atoms and one sulfur atom in the sufamide group form a saturated or unsaturated cyclic group; each cyclic group can further include at least one atom selected from the group consisting of oxygen, sulfur and nitrogen, and each cyclic group can be substituted; X.sup.1 is hydrogen or a hydroxy protecting group; X.sup.2 is hydrogen, a carboxy protecting group, an ammonio group, an alkali metal or an alkaline-earth metal; and Y.sup.2 is hydrogen or an amino protecting group.
Inventor(s): Nishitani; Yasuhiro (Osaka, JP), Irie; Tadashi (Osaka, JP)
Assignee: Shionogi Seiyaku Kabushiki Kaisha (Osaka, JP)
Application Number:07/929,961
Patent Claim Types:
see list of patent claims
Compound; Use;
Patent landscape, scope, and claims:

Detailed Analysis of the Scope and Claims of United States Patent 5,317,016

Introduction

United States Patent 5,317,016, titled "Pyrrolidylthiocarbapenem derivative," is a patent that describes a novel carbapenem derivative with enhanced antibacterial properties. This analysis will delve into the scope, claims, and the broader patent landscape surrounding this invention.

Background of the Patent

The patent, issued on May 31, 1994, addresses the need for a carbapenem derivative with a wider range of antibacterial spectrum and stronger antimicrobial activity. The invention is part of the broader field of heterocyclic compounds, specifically those containing 1-azabicyclo [3.2.0] heptane ring systems, such as carbapenicillins and thienamycins[4].

Scope of the Invention

The patent describes a pyrrolidylthiocarbapenem derivative represented by specific chemical formulas (Formula I and Formula II). These formulas outline the structural components of the compound, including various substituents and cyclic groups. The invention encompasses not only the compounds themselves but also methods for producing these derivatives.

Chemical Structure

The pyrrolidylthiocarbapenem derivative is characterized by its complex chemical structure, which includes:

  • R1, R2, R3, and R4: These can be hydrogen, lower alkyl groups (which can be substituted), or amino protecting groups. Additionally, these groups can form saturated or unsaturated cyclic groups with nitrogen, sulfur, and oxygen atoms[4].
  • X1 and X2: These can be hydrogen, hydroxy protecting groups, carboxy protecting groups, ammonio groups, or alkali/alkaline-earth metal groups[4].

Method of Production

The patent also details a method for producing the pyrrolidine derivative, which involves specific chemical reactions and protecting groups to ensure the desired structural outcome[4].

Claims of the Patent

The claims of the patent are crucial as they define the scope of protection granted to the inventor.

Independent Claims

The patent includes several independent claims that focus on the chemical compounds and their production methods. For example:

  • Claim 1 describes the pyrrolidylthiocarbapenem derivative with specific substituents and cyclic groups.
  • Claim 2 outlines the method for producing the derivative, including the steps and reagents involved[4].

Dependent Claims

Dependent claims further specify the invention by detailing various aspects of the compound and its production, such as specific substituents, protecting groups, and reaction conditions. These claims narrow down the scope to ensure that the protection is tailored to the unique aspects of the invention.

Patent Landscape

Understanding the patent landscape is essential for assessing the impact and relevance of the patent.

Prior Art

The patent cites several prior art references related to heterocyclic compounds and carbapenem derivatives. This indicates that the invention builds upon existing knowledge but introduces novel elements that differentiate it from prior art[4].

Classification

The patent is classified under various categories, including C07D477/16 and C07D477/20, which pertain to heterocyclic compounds containing specific ring systems and sulfur atoms, respectively. This classification helps in identifying similar patents and understanding the broader technological context[4].

Global Dossier and Patent Family

Using tools like the Global Dossier provided by the USPTO, one can trace the patent family for this application, including related applications filed at participating IP Offices. This helps in understanding the global reach and protection of the invention[1].

Claim Coverage and Scope Concepts

To fully analyze the patent's scope, it is beneficial to use patent analytics tools.

Claim Coverage Matrix

A Claim Coverage Matrix can help identify which patents and claims are actively protecting the intellectual property related to this invention. This matrix categorizes patents by claims and scope concepts, making it easier to filter, search, and analyze large numbers of patent claims concurrently[3].

Claim Charts

Interactive claim charts generated by tools like ClaimScape® can be reviewed by technical experts to determine whether specific scope concepts are applicable to target products or methods. This helps in identifying gaps in current coverage and highlighting future design opportunities[3].

Practical Implications and Enforcement

Correct inventorship and the absence of deceptive intent are crucial for the enforceability of the patent. Errors in inventorship can lead to the patent being invalid and unenforceable, even if corrected later[2].

Key Takeaways

  • Novel Chemical Structure: The patent introduces a novel pyrrolidylthiocarbapenem derivative with enhanced antibacterial properties.
  • Detailed Claims: The patent includes specific claims that define the chemical compounds and their production methods.
  • Patent Landscape: The invention is part of a broader field of heterocyclic compounds and is classified under specific categories.
  • Global Protection: The patent's global reach can be understood through tools like the Global Dossier.
  • Patent Analytics: Tools like Claim Coverage Matrix and Claim Charts are essential for analyzing the patent's scope and identifying gaps in coverage.

FAQs

What is the main subject matter of United States Patent 5,317,016?

The main subject matter is a pyrrolidylthiocarbapenem derivative with enhanced antibacterial properties.

How is the chemical structure of the derivative described in the patent?

The structure is described using specific chemical formulas (Formula I and Formula II), detailing various substituents and cyclic groups.

What are the key claims of the patent?

The key claims include descriptions of the chemical compounds and the methods for producing these derivatives.

How can one analyze the scope and claims of this patent?

Using patent analytics tools such as Claim Coverage Matrix and Claim Charts can help in analyzing the scope and identifying gaps in coverage.

Why is correct inventorship important for this patent?

Correct inventorship is crucial to ensure the patent's enforceability, as errors or deceptive intent can render the patent invalid and unenforceable.

Sources

  1. USPTO: Search for patents - USPTO
  2. Oregon State University: Determining Inventorship for US Patent Applications
  3. SLWIP: Patent Analytics | Intellectual Property Law
  4. Google Patents: US5317016A - Pyrrolidylthiocarbapenem derivative - Google Patents
  5. USA.gov: U.S. Patent and Trademark Office (USPTO) | USAGov

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Drugs Protected by US Patent 5,317,016

ApplicantTradenameGeneric NameDosageNDAApproval DateTETypeRLDRSPatent No.Patent ExpirationProductSubstanceDelist Req.Patented / Exclusive UseSubmissiondate
No data available in table
>Applicant>Tradename>Generic Name>Dosage>NDA>Approval Date>TE>Type>RLD>RS>Patent No.>Patent Expiration>Product>Substance>Delist Req.>Patented / Exclusive Use>Submissiondate
Showing 0 to 0 of 0 entries

Foreign Priority and PCT Information for Patent: 5,317,016

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Japan3-207972Aug 20, 1991
Japan4-35366Feb 21, 1992

International Family Members for US Patent 5,317,016

CountryPatent NumberEstimated ExpirationSupplementary Protection CertificateSPC CountrySPC Expiration
European Patent Office 0528678 ⤷  Try for Free CA 2009 00003 Denmark ⤷  Try for Free
European Patent Office 0528678 ⤷  Try for Free 91519 Luxembourg ⤷  Try for Free
European Patent Office 0528678 ⤷  Try for Free 300374 Netherlands ⤷  Try for Free
>Country>Patent Number>Estimated Expiration>Supplementary Protection Certificate>SPC Country>SPC Expiration
Showing 1 to 3 of 3 entries

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