Details for Patent: 5,438,071
✉ Email this page to a colleague
Summary for Patent: 5,438,071
Title: | Stable porfimer sodium compositions and methods for their manufacture |
Abstract: | A storage stable porfimer sodium (polyhematoporphyrin ether/ester) composition useful in the photodynamic therapy of cancer and other conditions is provided. The composition is characterized in that the percentage of ester linked porphyrin oligomers is less than 10% of the composition. Improved processes for preparing such compositions are also provided wherein acetylated hematoporphyrin is treated with alkali for sufficient time and temperature to reduce the amount of porphyrin oligomers joined by ester linkages to less than 10% of the composition. |
Inventor(s): | Clauss; Steven L. (Manville, NJ), Pastel; Michael J. (Highland Mills, NY), Zawadzki; Rainer K. (Wuhan, CN) |
Assignee: | American Cyanamid Company (Stamford, CT) |
Application Number: | 08/075,227 |
Patent Claim Types: see list of patent claims | Composition; Compound; Use; |
Drugs Protected by US Patent 5,438,071
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
International Family Members for US Patent 5,438,071
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
---|---|---|---|---|---|
Austria | 150968 | ⤷ Sign Up | |||
Canada | 2094974 | ⤷ Sign Up | |||
Germany | 69309340 | ⤷ Sign Up | |||
Denmark | 0568323 | ⤷ Sign Up | |||
>Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |