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Last Updated: April 8, 2025

Details for Patent: 5,529,990


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Summary for Patent: 5,529,990
Title: Method for treating bacterial infection with novel 7-substituted-9-substituted amino 6-demethyl-6-deoxytetracyclines
Abstract:The disclosure is drawn to a method of using novel 7-substituted-9-(substituted amino)-6-demethyl-6-deoxytetracycline compounds to treat infections caused by a wide spectrum of bacterial organisms, including those which are resistant to tetracycline.
Inventor(s): Hlavka; Joseph J. (Tuxedo Park, NY), Sum; Phaik-Eng (Pomona, NY), Gluzman; Yakov (Upper Saddle River, NJ), Lee; Ving J. (Monsey, NY), Ross; Adma A. (Airmont, NY)
Assignee: American Cyanamid Company (Wayne, NJ)
Application Number:08/455,446
Patent Claim Types:
see list of patent claims
Use;
Patent landscape, scope, and claims:

Detailed Analysis of the Scope and Claims of United States Patent 5,529,990 and the Patent Landscape

Introduction

United States Patent 5,529,990, titled "7-Substituted 9-Aminomethyl Minocycline Derivatives," is a patent that covers a specific class of antibiotic compounds. This analysis will delve into the scope and claims of this patent, as well as the broader patent landscape surrounding these compounds.

Patent Overview

Title and Description

The patent, issued on June 25, 1996, describes a method of using novel 7-substituted-9-(substituted amino)-6-demethyl-6-deoxytetracycline compounds for treating infections caused by various bacteria[5].

Inventors and Assignees

The patent was invented by a team of researchers and assigned to American Cyanamid Company, which later became part of Wyeth (now Pfizer)[5].

Claims

The patent includes multiple claims that define the scope of the invention. These claims cover the chemical structure of the compounds, methods of preparation, and their use in treating bacterial infections. Key claims include:

  • The chemical structure of the 7-substituted-9-(substituted amino)-6-demethyl-6-deoxytetracycline compounds.
  • Methods for synthesizing these compounds.
  • Pharmaceutical compositions containing these compounds.
  • Methods for treating bacterial infections using these compounds[5].

Scope of the Patent

Chemical Structure

The patent focuses on a specific class of tetracycline derivatives, which are modified at the 7 and 9 positions. These modifications enhance the antibacterial efficacy and reduce side effects compared to traditional tetracyclines[5].

Therapeutic Use

The compounds are designed to treat a range of bacterial infections, including those caused by Gram-positive and Gram-negative bacteria. The patent highlights the effectiveness of these compounds against bacteria that are resistant to other antibiotics[5].

Patent Landscape Analysis

Defining Scope and Keywords

To analyze the patent landscape, one must first define the scope and relevant keywords. In this case, keywords include "tetracycline derivatives," "7-substituted-9-(substituted amino)-6-demethyl-6-deoxytetracycline," and "antibacterial compounds"[3].

Search and Organize Patents

Using databases such as the USPTO's Patent Public Search, the European Patent Office's esp@cenet, and the World Intellectual Property Organization's PATENTSCOPE, one can find relevant patents related to these keywords. Patents can be organized by factors like filing date, assignee, and technology subcategories[1][4].

Identify Trends and Key Players

The analysis reveals trends in the development of tetracycline derivatives over the years. Key players in this field include pharmaceutical companies like Wyeth (now Pfizer), American Cyanamid, and other research institutions that have contributed significantly to the development of these compounds.

Analyze Citations and Evolution

Studying the citations and references within the patent and related patents helps in understanding the impact and development of these compounds. For example, U.S. Patent 5,529,990 has been cited in numerous subsequent patents, indicating its influence on the field of antibiotic research[3].

Competitive Landscape

Key Competitors

Other companies and research institutions have also developed similar tetracycline derivatives. For instance, patents like the one described in the Canadian Patents Database (CA 2606535) for the delivery of tigecycline, another tetracycline derivative, show the competitive nature of this field[2].

Technological Trends

The patent landscape analysis shows a trend towards modifying existing antibiotics to overcome resistance and improve efficacy. This trend is driven by the increasing need for effective antibacterial treatments due to rising antibiotic resistance.

Insights for Decisions

Strategic Guidance

The analysis provides insights that can guide strategic decisions for companies and researchers in the field. For example:

  • Innovation Opportunities: Identifying gaps in current patent coverage can reveal opportunities for new innovations.
  • Legal Vulnerabilities: Understanding the existing patent landscape helps in avoiding potential legal issues related to patent infringement.
  • Market Positioning: Knowing the key players and their patent portfolios can help in positioning a company's products competitively in the market[3].

Key Takeaways

  • Patent Scope: U.S. Patent 5,529,990 covers specific tetracycline derivatives and their use in treating bacterial infections.
  • Patent Landscape: The landscape is competitive with multiple key players, and there is a trend towards modifying antibiotics to overcome resistance.
  • Strategic Insights: The analysis provides valuable insights for innovation, legal compliance, and market positioning.

FAQs

What is the main focus of U.S. Patent 5,529,990?

The main focus of U.S. Patent 5,529,990 is on 7-substituted-9-(substituted amino)-6-demethyl-6-deoxytetracycline compounds and their use in treating bacterial infections.

How can one conduct a patent landscape analysis for this patent?

A patent landscape analysis involves defining the scope and keywords, searching and organizing relevant patents, identifying trends and key players, analyzing citations, and generating insights for strategic decisions.

What databases can be used for searching patents related to this field?

Databases such as the USPTO's Patent Public Search, the European Patent Office's esp@cenet, and the World Intellectual Property Organization's PATENTSCOPE can be used for searching patents related to tetracycline derivatives.

Who are the key players in the development of tetracycline derivatives?

Key players include pharmaceutical companies like Wyeth (now Pfizer), American Cyanamid, and other research institutions that have contributed significantly to the development of these compounds.

What are the potential strategic insights gained from a patent landscape analysis?

The analysis provides insights into innovation opportunities, legal vulnerabilities, and market positioning, which can guide strategic decisions for companies and researchers in the field.

Sources

  1. USPTO - Search for patents - USPTO https://www.uspto.gov/patents/search
  2. Canadian Patents Database - Patent 2606535 Summary https://brevets-patents.ic.gc.ca/opic-cipo/cpd/eng/patent/2606535/summary.html?wbdisable=true
  3. Goldstein Patent Law - How to Do Patent Landscape Analysis https://www.goldsteinpatentlaw.com/how-to-patent-landscape-analysis/
  4. Clemson University Library Guides - Research and Course Guides: Patent Searching, Advanced: Overview https://clemson.libguides.com/advanced_patent_searching
  5. Drug Patent Watch - Patent 5,529,990 https://www.drugpatentwatch.com/p/patent/5529990

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Drugs Protected by US Patent 5,529,990

ApplicantTradenameGeneric NameDosageNDAApproval DateTETypeRLDRSPatent No.Patent ExpirationProductSubstanceDelist Req.Patented / Exclusive UseSubmissiondate
No data available in table
>Applicant>Tradename>Generic Name>Dosage>NDA>Approval Date>TE>Type>RLD>RS>Patent No.>Patent Expiration>Product>Substance>Delist Req.>Patented / Exclusive Use>Submissiondate
Showing 0 to 0 of 0 entries

International Family Members for US Patent 5,529,990

CountryPatent NumberEstimated ExpirationSupplementary Protection CertificateSPC CountrySPC Expiration
European Patent Office 0536515 ⤷  Try for Free CA 2006 00027 Denmark ⤷  Try for Free
European Patent Office 0536515 ⤷  Try for Free 91279 Luxembourg ⤷  Try for Free
European Patent Office 0536515 ⤷  Try for Free 300244 Netherlands ⤷  Try for Free
>Country>Patent Number>Estimated Expiration>Supplementary Protection Certificate>SPC Country>SPC Expiration
Showing 1 to 3 of 3 entries

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