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Last Updated: November 24, 2024

Details for Patent: 5,543,152


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Summary for Patent: 5,543,152
Title: Sphingosomes for enhanced drug delivery
Abstract:Liposomal formulations having extended circulation time in vivo and increased drug retention are comprised of sphingomyelin and cholesterol and have an acidic intraliposomal pH. The formulations have enhanced stability and thus are used in methods which provide improved drug delivery and more effective treatment. The delivery of lipophilic drugs such as the vinca alkaloids, and particularly vincristine and vinblastine, to tumors is significantly improved.
Inventor(s): Webb; Murray S. (Vancouver, CA), Bally; Marcel B. (Bowen Island, CA), Mayer; Lawrence D. (North Vancouver, CA)
Assignee: Inex Pharmaceuticals Corporation (Vancouver, CA)
Application Number:08/263,603
Patent Claim Types:
see list of patent claims
Composition; Dosage form; Delivery; Compound; Process; Formulation;

Drugs Protected by US Patent 5,543,152

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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