Details for Patent: 5,575,987

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Summary for Patent: 5,575,987

Title:	Method of producing sustained-release microcapsules
Abstract:	A method of producing sustained-release microcapsules containing a biologically active substance from an W/O emulsion comprising an inner aqueous phase containing said biologically active substance and an external oil phase containing a biodegradable polymer, characterized in that microcapsules formed on microencapsulation of said biologically active substance with said biodegradable polymer are heated at a temperature not lower than the glass transition temperature of said biodegradable polymer but not so high as to cause aggregation of the microcapsules. This method enables the production of very useful sustained release microcapsules adapted to release a bologically active substance at a calculated rate over a protracted time period starting immediately following administration without an initial burst within one day following administration.
Inventor(s):	Kamei; Shigeru (Takarazuka, JP), Yamada; Minoru (Kawanishi, JP), Ogawa; Yasuaki (Ohyamazaki-cho, JP)
Assignee:	Takeda Chemical Industries, Ltd. (Osaka, JP)
Application Number:	08/562,634
Patent Claim Types: see list of patent claims	Dosage form;

Drugs Protected by US Patent 5,575,987

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

Foreign Priority and PCT Information for Patent: 5,575,987

Foriegn Application Priority Data
Foreign Country	Foreign Patent Number	Foreign Patent Date
Japan	4-234821	Sep 02, 1992

International Family Members for US Patent 5,575,987

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Canada	2105374	⤷ Sign Up
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Denmark	0586238	⤷ Sign Up
European Patent Office	0586238	⤷ Sign Up
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