| Abstract: | The present invention relates to a new compound of formula I ##STR1## with one of the symbols R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 representing OH, whereas the remaining symbols represent H; to a pharmaceutical composition containing the said compound, and to the use of said compound as anti-parasital, anti-bacterial, anti-fungal agent. The Prior Art Nitrothiazole compound PH 5776 (2-(acetolyloxy)-N-(5-nitro 2-thiazolyl) benzamide) is a compound of formula II ##STR2## in which R.sub.1 =O--COCH3 R.sub.2 =R.sub.3 =R.sub.4 =R.sub.5 =H The preparation and uses of this compound are disclosed in U.S. Pat. No. 3,950,351, as well as in publication made by Applicant. In U.S. Pat. No. 3,950,351, the compound of formula II is prepared by reacting ##STR3## This reaction is not suitable for the preparation of pure compound of formula I ##STR4## in which one of the symbols R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 represent OH, whereas the remaining symbols represent H. Moreover, contrary to what could be expected from the prior art, i.e. that the presence of an acyloxy group was necessary for rendering the compound active and efficient against bacteria, parasites, . . . , it has now been found that the compound of formula I ##STR5## with one of the symbols R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 representing OH, whereas the remaining symbols represent H; had an excellent efficiency against parasites, bacteria, fungus although it does not contain an acyloxy group. The compound of formula I had a substantially immediate action against parasite, fungus, bacteria. |
|
Patent landscape, scope, and claims: |
Understanding the Scope and Claims of United States Patent 5,578,621: A Detailed Analysis
Introduction
United States Patent 5,578,621, titled "Benzamide derivatives," is a patent that has significant implications in the fields of chemistry and pharmacology. This article will delve into the details of the patent, including its scope, claims, and the broader patent landscape in which it resides.
Background of the Patent
The patent in question, US 5,578,621, was granted for benzamide derivatives that exhibit substantial immediate action against parasites, fungi, and bacteria. This class of compounds is crucial in the development of pharmaceuticals and agricultural chemicals.
Scope of the Patent
Technological Field
The patent falls under the chemical and pharmaceutical technological fields. Specifically, it is classified within the broader category of organic chemistry, focusing on the synthesis and application of benzamide derivatives[2].
Applications
The benzamide derivatives described in the patent have multiple applications:
- Pharmaceuticals: These compounds are effective against a range of pathogens, making them valuable in the development of drugs for treating various infections.
- Agricultural Chemicals: Their efficacy against fungi and parasites also makes them suitable for use in agricultural settings to protect crops and livestock.
Claims of the Patent
Key Claims
The patent includes several key claims that define the scope of the invention:
- Chemical Structure: The patent specifies the chemical structure of the benzamide derivatives, including the specific moieties and functional groups that confer the desired biological activity.
- Synthesis Method: The claims also cover the methods for synthesizing these compounds, ensuring that the patent holder has control over the production process.
- Biological Activity: The claims highlight the biological activity of the compounds, including their immediate action against parasites, fungi, and bacteria[2].
Claim Analysis
Each claim in the patent is carefully crafted to ensure that it meets the criteria for patentability, including novelty, non-obviousness, and utility. Here’s a breakdown of what each type of claim might entail:
- Independent Claims: These claims stand alone and define the broadest scope of the invention. For example, Claim 1 might describe the general chemical structure of the benzamide derivatives.
- Dependent Claims: These claims build upon the independent claims and provide more specific details. For instance, Claim 2 might specify a particular method of synthesis or a specific application of the compound[3].
Patent Landscape
Technological Trends
The patent landscape for chemical and pharmaceutical inventions is dynamic and influenced by various technological trends:
- R&D Investment: Industries with high R&D investments, such as the computer and electronics manufacturing sector, also show significant patenting activity in related fields. However, the chemical and pharmaceutical sectors have their own unique trends, with a focus on innovation in drug discovery and development[1].
- Global Comparisons: The World Intellectual Property Organization (WIPO) classification system helps in comparing patent trends globally. For instance, electrical engineering and mechanical engineering patents dominate the USPTO grants, but chemical and pharmaceutical patents are also significant, especially in the context of global health and agricultural needs[1].
Industry Affiliation
The industry affiliation of inventors and assignees plays a crucial role in the patent landscape:
- Business Sector: The majority of patents, including those in the chemical and pharmaceutical fields, are assigned to businesses. This indicates that corporate R&D efforts are a driving force behind innovation in these sectors[1].
- Academic and Government Sector: While the academic and government sectors receive a smaller share of patents, their contributions are vital in advancing basic research and translating it into practical applications.
Recent Developments and Guidance
AI and Patent Eligibility
Although the patent in question does not involve AI, recent updates from the USPTO on AI-related inventions provide valuable insights into the evolving patent landscape:
- USPTO Guidance: The 2024 USPTO guidance update on AI patents clarifies the process for determining the patent eligibility of AI-related inventions. This guidance includes new examples that illustrate how claims involving AI can meet the eligibility criteria by demonstrating tangible benefits and improvements in technology[4].
Impact and Implications
Market and Research Implications
The patent on benzamide derivatives has significant implications for both market and research:
- Market Impact: The development of these compounds can lead to new pharmaceuticals and agricultural chemicals, potentially disrupting existing markets and creating new opportunities.
- Research Implications: The patent encourages further research into the synthesis and application of benzamide derivatives, driving innovation in the field.
Key Takeaways
- Scope and Claims: The patent covers specific benzamide derivatives with immediate action against parasites, fungi, and bacteria, including their synthesis and applications.
- Technological Field: The patent is classified within the chemical and pharmaceutical fields.
- Industry Affiliation: The majority of such patents are assigned to businesses, with significant R&D investments.
- Recent Developments: The USPTO's guidance on AI patents, while not directly relevant, highlights the evolving nature of patent eligibility criteria.
FAQs
-
What is the main subject of United States Patent 5,578,621?
- The main subject is benzamide derivatives with substantial immediate action against parasites, fungi, and bacteria.
-
What are the primary applications of the compounds described in the patent?
- The primary applications include pharmaceuticals and agricultural chemicals.
-
How are the claims in the patent structured?
- The claims are structured to include independent claims defining the broad scope and dependent claims providing more specific details.
-
What is the significance of the USPTO's 2024 guidance update on AI patents?
- The update clarifies the process for determining the patent eligibility of AI-related inventions, providing examples and eligibility analysis.
-
Who typically receives patents in the chemical and pharmaceutical sectors?
- The majority of patents in these sectors are assigned to businesses, reflecting their significant R&D investments.
Sources
- National Science Foundation. Invention: U.S. and Comparative Global Trends. January 15, 2020.
- PubChem. Benzamide derivatives - Patent US-5578621-A. Google Patents.
- United States Patent and Trademark Office. Patent Claims Research Dataset. August 28, 2017.
- Mintz. Understanding the 2024 USPTO Guidance Update on AI Patent. July 25, 2024.
More… ↓
⤷ Try for Free
|
