Details for Patent: 5,604,229
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Summary for Patent: 5,604,229
Title: | 2-amino-1,3-propanediol compound and immunosuppressant |
Abstract: | 2-Amino-1,3-propanediol compounds of the formula (I) ##STR1## wherein R is an optionally substituted straight- or branched carbon chain, an optionally substituted aryl, an optionally substituted cycloalkyl or the like, and R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are the same or different and each is a hydrogen, an alkyl, an aralkyl, an acyl or an alkoxycarbonyl, pharmaceutically acceptable salts thereof and immunosuppressants comprising these compounds as active ingredients. The 2-amino-1,3-propanediol compounds of the present invention show immunosuppressive action and are useful for suppressing rejection in organ or bone marrow tranplantation, prevention and treatment of autoimmune diseases or as reagents for use in medicinal and pharmaceutical fields. |
Inventor(s): | Fujita; Tetsuro (Muko, JP), Sasaki; Shigeo (Kobe, JP), Yoneta; Masahiko (Kobe, JP), Mishina; Tadashi (Iruma, JP), Adachi; Kunitomo (Iruma, JP), Chiba; Kenji (Iruma, JP) |
Assignee: | Yoshitomi Pharmaceutical Industries, Ltd. (Osaka, JP) Taito Co., Ltd. (Tokyo, JP) |
Application Number: | 08/244,942 |
Patent Claim Types: see list of patent claims | Compound; Use; | More… ↓ |
Drugs Protected by US Patent 5,604,229
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
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>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
Foreign Priority and PCT Information for Patent: 5,604,229
Foriegn Application Priority Data | ||
Foreign Country | Foreign Patent Number | Foreign Patent Date |
Japan | 4-283281 | Oct 21, 1992 |
Japan | 5-179427 | Jul 20, 1993 |
PCT Information | |||
PCT Filed | October 18, 1993 | PCT Application Number: | PCT/JP93/01515 |
PCT Publication Date: | April 28, 1994 | PCT Publication Number: | WO94/08943 |
International Family Members for US Patent 5,604,229
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
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European Patent Office | 0627406 | ⤷ Subscribe | C300488 | Netherlands | ⤷ Subscribe |
European Patent Office | 0627406 | ⤷ Subscribe | SPC/GB11/026 | United Kingdom | ⤷ Subscribe |
European Patent Office | 0627406 | ⤷ Subscribe | 11C0021 | France | ⤷ Subscribe |
>Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |