United States Patent 5,633,272: A Detailed Analysis of Scope, Claims, and Patent Landscape
Introduction
United States Patent 5,633,272, titled "Substituted isoxazoles for the treatment of inflammation," is a significant patent in the field of pharmaceuticals, particularly in the treatment of inflammatory disorders. This analysis will delve into the scope, claims, and the broader patent landscape surrounding this invention.
Patent Overview
Publication and Authority
The patent, US5633272A, was granted by the United States Patent and Trademark Office (USPTO) and is now expired, having completed its lifetime[4].
Inventive Subject Matter
The patent describes a class of substituted isoxazolyl compounds designed for the treatment of inflammation and inflammation-related disorders. These compounds are highlighted for their anti-inflammatory properties with minimal side effects.
Scope of the Patent
Claim Analysis
The scope of a patent is largely defined by its claims. For US5633272A, the claims specify the chemical structure and composition of the substituted isoxazoles, including their functional groups and molecular arrangements. Here are some key aspects:
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Independent Claims: These claims define the broadest scope of the invention. For example, Claim 1 might specify a general formula for the substituted isoxazoles, while subsequent claims narrow down to specific embodiments or variations of the compounds[4].
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Dependent Claims: These claims build upon the independent claims, providing more detailed descriptions of specific aspects of the invention, such as particular substituents or methods of preparation.
Metrics for Patent Scope
Research has shown that metrics such as independent claim length and independent claim count can be used to measure patent scope. Narrower claims, as seen in this patent, are often associated with a higher probability of grant and a shorter examination process[3].
Claims and Their Significance
Chemical Structure
The claims in US5633272A focus on the specific chemical structures of the substituted isoxazoles. For instance, the patent mentions compounds such as 3-(2-hydroxyphenyl)isoxazoles and 5-piperazinyl-3,4-diaryl-isoxazoles, which are known for their anti-inflammatory properties[4].
Therapeutic Use
The claims also emphasize the therapeutic use of these compounds, specifically their application in treating inflammatory disorders. This includes conditions such as arthritis, where these compounds can act as cyclooxygenase inhibitors, reducing inflammation.
Prior Art and Related Patents
International Context
The patent landscape for anti-inflammatory agents is rich with prior art. For example, European Patent EP 26928 describes 3,4-diaryl-isoxazole-5-acetic acids with anti-inflammatory activity, while World Intellectual Property Organization (WIPO) publications WO 92/05162 and WO 92/19604 discuss similar compounds with medicinal use[4].
Domestic Context
In the United States, other patents and patent applications have also addressed similar anti-inflammatory compounds. For instance, the dispersible formulation of an anti-inflammatory agent described in US-2005004098-A1 shows the ongoing innovation in this field[5].
Patent Search and Analysis Tools
To understand the broader patent landscape, several tools and resources are available:
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Patent Public Search: This tool, provided by the USPTO, allows for comprehensive searches of prior art and related patents. It replaces legacy tools like PubEast and PubWest and offers enhanced access to prior art[1].
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Global Dossier: This service provides access to the file histories of related applications from participating IP Offices, helping to identify patent families and related citations[1].
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Common Citation Document (CCD): This application consolidates citation data from multiple IP Offices, facilitating a more integrated view of the global patent landscape[1].
Impact on Innovation and Litigation
Patent Quality and Scope
The debate over patent quality often revolves around the breadth and clarity of patent claims. Patents with narrower, clearer claims, like those in US5633272A, are generally seen as more valid and less likely to lead to litigation. This is because they provide a clearer boundary of what is protected, reducing the likelihood of overlapping claims and disputes[3].
Licensing and Litigation Costs
Broader or overly broad patents can increase licensing and litigation costs, potentially stifling innovation. In contrast, patents with well-defined claims, such as US5633272A, can facilitate more efficient licensing and reduce the risk of costly legal battles.
Conclusion
United States Patent 5,633,272 represents a significant contribution to the field of anti-inflammatory treatments. The patent's scope, defined by its claims, highlights specific substituted isoxazolyl compounds with therapeutic applications. Understanding this patent within the broader patent landscape, using tools like the Patent Public Search and Global Dossier, is crucial for innovators and legal practitioners alike.
Key Takeaways
- Specific Claims: The patent's claims are narrowly defined, specifying the chemical structures and therapeutic uses of the substituted isoxazoles.
- Prior Art: The invention builds upon a rich prior art landscape, including international and domestic patents related to anti-inflammatory agents.
- Patent Tools: Utilizing tools like Patent Public Search and Global Dossier can help in understanding the patent's position within the global patent landscape.
- Impact on Innovation: Narrower, clearer claims can reduce litigation costs and facilitate innovation by providing clear boundaries of protection.
FAQs
What is the main subject matter of US Patent 5,633,272?
The main subject matter is a class of substituted isoxazolyl compounds used for the treatment of inflammation and inflammation-related disorders.
How can one search for related patents to US5633272A?
One can use the USPTO's Patent Public Search tool or the Global Dossier service to search for related patents and understand the broader patent landscape.
What are the benefits of narrower patent claims?
Narrower patent claims are associated with a higher probability of grant, a shorter examination process, and reduced litigation costs, as they provide clearer boundaries of protection.
How does prior art influence the scope of a patent?
Prior art can limit the scope of a patent by establishing what is already known in the field, thus requiring the patent claims to be more specific and innovative to be granted.
What tools are available for analyzing the global patent landscape?
Tools such as the Patent Public Search, Global Dossier, and Common Citation Document (CCD) are available for analyzing the global patent landscape and understanding the position of a patent within it.
Sources
- USPTO: Search for patents - USPTO.
- ACUS: U.S. Patent Small Claims Court.
- SSRN: Patent Claims and Patent Scope.
- Google Patents: US5633272A - Substituted isoxazoles for the treatment of inflammation.
- PubChem: Dispersible formulation of an anti-inflammatory agent - Patent US-2005004098-A1.
