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Last Updated: December 22, 2024

Details for Patent: 5,663,159


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Summary for Patent: 5,663,159
Title: Prodrugs of phosphonates
Abstract:There are disclosed novel oral prodrugs of phosphonate nucleotide analogs which are hydrolyzable under physiological conditions to yield compounds which are useful as antiviral agents, especially as agents effective against RNA and DNA viruses. They may also find use as antitumor agents.
Inventor(s): Starrett, Jr.; John E. (Middletown, CT), Mansuri; Muzammil M. (Cheshire, CT), Martin; John C. (Cheshire, CT), Tortolani; David R. (Meriden, CT), Bronson; Joanne J. (Madison, CT)
Assignee: Institute of Organic Chemistry and Biochemistry of the Academy of Sciences of the Czech Republic (CZ) N/A (BE) Rega Stichting v.z.w. (
Application Number:08/320,632
Patent Claim Types:
see list of patent claims
Compound; Composition; Use;
Patent landscape, scope, and claims:

Analyzing the Scope and Claims of United States Patent 5,663,159: A Comprehensive Guide

Introduction

Understanding the scope and claims of a patent is crucial for navigating the complex landscape of intellectual property. This article will delve into the details of United States Patent 5,663,159, titled "Prodrugs of phosphonates," to provide a thorough analysis of its claims, scope, and implications.

Overview of the Patent

US Patent 5,663,159 was granted for "Prodrugs of phosphonates," a invention related to the use of phosphonate compounds as prodrugs, which are inactive derivatives of a drug that become active in the body. Here is a brief overview:

  • Publication Number: US5663159A
  • Priority Date: August 12, 1994
  • Grant Date: September 2, 1997
  • Assignees: Gilead Sciences, Inc.[4]

Claims Analysis

The claims of a patent are its most critical component, as they define the scope of protection granted by the patent.

Independent Claims

Independent claims stand alone and do not rely on other claims for their validity. For US Patent 5,663,159, the independent claims typically include:

  • Claim 1: This claim usually defines the broadest scope of the invention, such as the composition of the prodrug.
  • Claim 2-5: These claims may narrow down the scope by specifying particular aspects of the prodrug, such as its structure, method of preparation, or specific uses.

Dependent Claims

Dependent claims build upon the independent claims and further limit the scope. For example:

  • Claim 6: This might specify a particular type of phosphonate compound or a specific method of administering the prodrug.

Claim Scope

The scope of the claims determines what is protected by the patent. In this case, the claims cover various aspects of the prodrugs, including their chemical structure, synthesis methods, and therapeutic applications. Here’s a more detailed look:

  • Chemical Structure: The claims specify the particular phosphonate compounds and their derivatives that are protected.
  • Synthesis Methods: Methods for preparing these prodrugs are also covered.
  • Therapeutic Applications: The claims may include specific uses, such as inhibiting tumor growth or treating viral infections[4].

Scope of the Patent

The scope of a patent is defined by its claims and is crucial for understanding what is protected and what is not.

Scope Concepts

To analyze the scope, it is helpful to categorize the claims by overarching scope concepts. This can include:

  • Chemical Composition: The specific phosphonate compounds and their derivatives.
  • Method of Preparation: The processes used to synthesize these compounds.
  • Therapeutic Use: The specific medical applications of the prodrugs[5].

Claim Coverage Matrix

A Claim Coverage Matrix can be used to visualize which patents and claims are actively protecting the intellectual property. For US Patent 5,663,159, this matrix would show how the claims cover different aspects of the prodrugs, highlighting any gaps or opportunities in the patent landscape[5].

Patent Landscape Analysis

Analyzing the patent landscape involves looking at the broader context of related patents and how they interact.

Related Patents

The patent landscape for phosphonate prodrugs includes other patents related to similar compounds and their applications. Tools like the Patent Public Search and Global Dossier can be used to identify related applications and their status across different jurisdictions[1].

Citation Data

The Common Citation Document (CCD) application can provide a single point of access to citation data related to the patent family, helping to identify prior art and the relevance of other patents in the field[1].

Practical Applications and Implications

Understanding the scope and claims of US Patent 5,663,159 has several practical implications:

  • Innovation and Development: Knowing the protected aspects of the prodrugs can guide further research and development, ensuring that new inventions do not infringe on existing patents.
  • Licensing and Collaboration: Companies can use this information to negotiate licensing agreements or collaborations, ensuring they have the necessary permissions to use the protected technology.
  • Competitive Analysis: Analyzing the patent landscape helps companies understand their competitors' positions and identify potential gaps in their own intellectual property portfolio[5].

Legal Status and Expiration

The legal status of a patent is crucial for determining its current validity.

  • US Patent 5,663,159 has expired, as indicated by its legal status. This means that the protected technology is now in the public domain and can be used without infringing on the original patent[4].

Conclusion

Understanding the scope and claims of US Patent 5,663,159 is essential for anyone working in the field of pharmaceuticals, particularly those involved in the development of prodrugs. Here are the key takeaways:

  • Claims Define Scope: The claims of the patent define what is protected and what is not.
  • Scope Concepts: Categorizing claims by scope concepts helps in analyzing the patent landscape.
  • Patent Landscape: Analyzing related patents and citation data provides a broader understanding of the intellectual property environment.
  • Practical Implications: Understanding the patent's scope and claims guides innovation, licensing, and competitive analysis.
  • Legal Status: The patent has expired, making the technology publicly available.

Key Takeaways

  • Claims Analysis: Independent and dependent claims define the scope of protection.
  • Scope Concepts: Categorize claims by chemical composition, method of preparation, and therapeutic use.
  • Patent Landscape: Use tools like Patent Public Search and Global Dossier to identify related patents.
  • Practical Applications: Guide innovation, licensing, and competitive analysis.
  • Legal Status: The patent has expired.

FAQs

  1. What is the main subject of US Patent 5,663,159?

    • The main subject is prodrugs of phosphonates, specifically their composition, synthesis, and therapeutic applications.
  2. How do you analyze the scope of a patent?

    • Analyze the claims, categorize them by scope concepts, and use tools like Claim Coverage Matrix and Patent Public Search.
  3. What is the significance of the Common Citation Document (CCD)?

    • The CCD provides a single point of access to citation data related to the patent family, helping to identify prior art and relevance of other patents.
  4. Why is it important to know the legal status of a patent?

    • Knowing the legal status helps determine if the patent is still in force or has expired, affecting how the protected technology can be used.
  5. How can companies use patent analytics for their benefit?

    • Companies can use patent analytics to identify gaps in their patent coverage, track patents by claims and scope concepts, and guide innovation and licensing strategies[5].

More… ↓

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Drugs Protected by US Patent 5,663,159

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 5,663,159

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 0481214 ⤷  Subscribe 91036 Luxembourg ⤷  Subscribe
European Patent Office 0481214 ⤷  Subscribe 300131 Netherlands ⤷  Subscribe
European Patent Office 0481214 ⤷  Subscribe SPC/GB03/030 United Kingdom ⤷  Subscribe
European Patent Office 0481214 ⤷  Subscribe C300131 Netherlands ⤷  Subscribe
European Patent Office 0481214 ⤷  Subscribe 03C0034 France ⤷  Subscribe
Austria 167679 ⤷  Subscribe
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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