United States Patent 5,676,968: A Detailed Analysis of Scope and Claims
Introduction
United States Patent 5,676,968, titled "Transdermal therapeutic systems with crystallization inhibitors," is a significant patent in the field of pharmaceuticals, particularly in the development of transdermal drug delivery systems. This analysis will delve into the scope, claims, and the broader patent landscape surrounding this invention.
Background
The patent, issued on October 14, 1997, describes a transdermal therapeutic system designed to deliver active ingredients through the skin, with a focus on preventing crystallization of the active compound within the system. This innovation is crucial for maintaining the efficacy and stability of the therapeutic system.
Scope of the Invention
Overview
The patent covers a transdermal therapeutic system that includes a matrix containing an active ingredient, a crystallization inhibitor, and optionally a penetration enhancer. The system is designed to ensure that the active ingredient remains in a stable, non-crystalline form, thereby enhancing its therapeutic effect[4].
Key Components
- Active Ingredient: The patent specifies various active ingredients that can be used, including compounds like steroid hormones and other therapeutic agents.
- Crystallization Inhibitor: This component is critical as it prevents the crystallization of the active ingredient, ensuring consistent drug delivery.
- Penetration Enhancer: Optional, this component helps in increasing the permeability of the skin to the active ingredient.
- Matrix Material: The matrix can be made from various substances such as polymers, adhesives, and protective layers.
Claims
The patent includes several claims that define the scope of the invention:
Independent Claims
- Claim 1 describes the transdermal therapeutic system comprising a matrix containing an active ingredient and a crystallization inhibitor.
- Claim 2 specifies the inclusion of a penetration enhancer in the system.
- Claim 3 details the composition of the matrix material, including adhesives and protective layers[4].
Dependent Claims
These claims further elaborate on the specific components and their roles:
- Claims 4-6 describe different types of active ingredients that can be used.
- Claims 7-10 specify various crystallization inhibitors and their combinations.
- Claims 11-15 detail the types of penetration enhancers and their applications[4].
Patent Landscape
Prior Art
The patent builds upon existing knowledge in the field of transdermal drug delivery. Prior art keywords include terms like "active ingredient," "matrix," "adhesive," and "penetration enhancer," indicating the evolution of technology in this area[4].
Related Patents
Other patents in the field of transdermal drug delivery systems often focus on similar components and challenges, such as maintaining the stability of the active ingredient and enhancing skin permeability. For instance, patents related to the use of different types of penetration enhancers or novel matrix materials are common[1].
International Context
The global patent landscape for transdermal therapeutic systems is extensive. Databases such as those provided by the European Patent Office (EPO), Japan Patent Office (JPO), and the World Intellectual Property Organization (WIPO) offer access to international patent applications and granted patents in this field. Tools like the Common Citation Document (CCD) help in consolidating prior art citations from multiple offices, facilitating a more comprehensive search[1].
Patent Analytics and Claim Coverage
Claim Coverage Matrix
To understand the full scope of protection provided by this patent, a Claim Coverage Matrix can be useful. This matrix helps in identifying which claims and scope concepts are actively protecting the intellectual property. For example, categorizing claims by scope concepts such as "crystallization inhibition" or "penetration enhancement" can provide a clear picture of the patent's coverage and potential gaps[3].
Claim Charts
Interactive claim charts generated through tools like ClaimScape® can help technical experts and management review the patent coverage. These charts can highlight areas where the current claim coverage is insufficient and identify future design opportunities. This approach ensures that the patent claims are aligned with the company's current and future technological directions[3].
Legal Status and Expiration
The patent has expired, as indicated by its legal status. This means that the technology described in the patent is now in the public domain, and anyone can use it without infringing on the original patent rights. However, it is important to note that other related patents may still be in force, and any new developments or improvements could be subject to new patent applications[4].
Practical Applications and Impact
The invention described in this patent has significant practical applications in the pharmaceutical industry. Transdermal therapeutic systems with crystallization inhibitors can improve the efficacy and stability of drug delivery, enhancing patient outcomes. This technology can be applied to a wide range of therapeutic agents, making it a valuable contribution to the field.
Key Takeaways
- Scope and Claims: The patent covers a transdermal therapeutic system with a matrix containing an active ingredient, a crystallization inhibitor, and optionally a penetration enhancer.
- Key Components: The system includes critical components such as the active ingredient, crystallization inhibitor, penetration enhancer, and matrix material.
- Patent Landscape: The patent is part of a broader landscape of transdermal drug delivery systems, with related patents and international applications.
- Patent Analytics: Tools like Claim Coverage Matrix and interactive claim charts are essential for understanding and managing the patent's coverage.
- Legal Status: The patent has expired, making the technology publicly available.
FAQs
Q: What is the main innovation of United States Patent 5,676,968?
A: The main innovation is the inclusion of a crystallization inhibitor in a transdermal therapeutic system to prevent the crystallization of the active ingredient, ensuring consistent drug delivery.
Q: What are the key components of the transdermal therapeutic system described in the patent?
A: The key components include the active ingredient, crystallization inhibitor, penetration enhancer, and matrix material.
Q: How does the patent landscape look for transdermal drug delivery systems?
A: The landscape is extensive with numerous related patents and international applications. Tools like the Common Citation Document (CCD) help in consolidating prior art citations.
Q: What is the significance of a Claim Coverage Matrix in patent analytics?
A: A Claim Coverage Matrix helps in identifying which claims and scope concepts are actively protecting the intellectual property, highlighting gaps and future design opportunities.
Q: What is the current legal status of United States Patent 5,676,968?
A: The patent has expired, making the technology described in the patent publicly available.
Sources
- USPTO: Search for patents - USPTO.
- Unified Patents: JP-5676968-B2 - 画像処理装置及び画像処理方法.
- SLWIP: Patent Analytics | Intellectual Property Law.
- Google Patents: US5676968A - Transdermal therapeutic systems with crystallization inhibitors.
- Casetext: Ex Parte 5676968 et al, 90012693.
