Details for Patent: 5,686,060

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Summary for Patent: 5,686,060

Title:	Stable microbubble suspensions comprising saturated phospholipids for ultrasound echography
Abstract:	Disclosed are injectable suspensions of gas filled microbubbles in an aqueous carrier liquid usable as contrast agents in ultrasonic echography. The suspensions comprise amphipathic compounds of which at least one may be a laminarized phospholipid as a stabilizer of the microbubbles against collapse with time and pressure. The concentration of phospholipids in the carrier liquid is below 0.01% wt but is at least equal to or above that at which phospholipid molecules are present solely at the gas microbubble-liquid interface. Also disclosed is a method of preparation of the stable suspensions of air or gas filled microbubbles.
Inventor(s):	Schneider; Michel (Troinex, CH), Brochot; Jean (Feigeres, FR), Puginier; Jerome (Le Chable-Beaumont, FR), Yan; Feng (Meyrin, CH)
Assignee:	Bracco International BV (NL)
Application Number:	08/420,677
Patent Claim Types: see list of patent claims	Composition;

Drugs Protected by US Patent 5,686,060

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European Patent Office	0619743	⤷ Sign Up	C300061	Netherlands	⤷ Sign Up
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