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Last Updated: April 21, 2025

Details for Patent: 5,792,753


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Summary for Patent: 5,792,753
Title: Compositions comprising hyaluronic acid and prostaglandin-synthesis-inhibiting drugs
Abstract:A topically administrable pharmaceutical composition is disclosed which comprises a therapeutically effective amount of a drug which inhibits prostaglandin synthesis, and an amount of a form of hyaluronic acid sufficient to transport the composition through the skin into the epidermis or dermis where the composition remains until discharged via the lymphatic system, wherein (a) the drug is 1-5% by weight of the composition, and (b) the form of hyaluronic acid is 1-3% by weight of the composition, has a molecular weight greater than about 150,000 daltons and less than 750,000 daltons, and is selected from the group consisting of hyaluronic acid and salts thereof.
Inventor(s): Falk; Rudolf Edgar (Toronto, CA), Asculai; Samuel Simon (Toronto, CA)
Assignee: Hyal Pharmaceutical Corporation (Mississauga, CA)
Application Number:08/018,508
Patent Claim Types:
see list of patent claims
Composition; Dosage form;
Patent landscape, scope, and claims:

United States Patent 5,792,753: A Detailed Analysis of Scope, Claims, and Patent Landscape

Introduction

United States Patent 5,792,753, titled "Compositions comprising hyaluronic acid and prostaglandin-synthesis-inhibiting drugs," was issued on August 11, 1998, to inventors Falk et al. This patent is significant in the pharmaceutical industry, particularly in the development of topical compositions for various medical treatments. Here, we will delve into the scope, claims, and the broader patent landscape surrounding this invention.

Patent Overview

Title and Inventors

The patent, titled "Compositions comprising hyaluronic acid and prostaglandin-synthesis-inhibiting drugs," was invented by Falk et al. and assigned to Nycomed US Inc. and Jagotec AG[2].

Issue Date and Patent Number

The patent was issued on August 11, 1998, and bears the number 5,792,753[2].

Scope of the Invention

Description

The patent describes pharmaceutical compositions that combine hyaluronic acid with prostaglandin-synthesis-inhibiting drugs. These compositions are designed for topical administration and are intended to treat various conditions, including skin disorders and inflammatory diseases. Hyaluronic acid, known for its moisturizing and protective properties, is combined with drugs that inhibit prostaglandin synthesis, which are often used to reduce inflammation and pain[5].

Applications

The compositions covered by this patent can be used in a variety of medical and cosmetic applications. For instance, they can be formulated as creams, gels, or ointments for the treatment of skin conditions such as acne, psoriasis, and dermatitis. The combination of hyaluronic acid and anti-inflammatory drugs enhances the therapeutic efficacy and reduces potential side effects associated with the use of these drugs alone[5].

Claims of the Patent

Independent Claims

The patent includes several independent claims that define the scope of the invention. These claims typically describe the composition, its components, and the method of preparation. For example, Claim 1 might describe a pharmaceutical composition comprising a therapeutically effective amount of a prostaglandin-synthesis-inhibiting drug and hyaluronic acid, along with suitable excipients for topical administration[5].

Dependent Claims

Dependent claims further specify the invention by detailing specific aspects such as the concentration of the active ingredients, the type of prostaglandin-synthesis-inhibiting drugs used, and the method of application. These claims help to narrow down the scope and provide additional protection for specific embodiments of the invention[5].

Patent Landscape

Related Patents

The inventors, Falk et al., have been granted several related patents that expand on the concept of combining hyaluronic acid with various drugs. For example, United States Patents 5,639,738, 5,852,002, 5,914,322, and 5,929,048 also relate to treatments involving hyaluronic acid and other therapeutic agents[2].

Global Dossier and Patent Family

Using the Global Dossier service provided by the USPTO, one can access the file histories of related applications from participating IP Offices. This service helps in understanding the global patent family for this specific application, including all related applications filed at participating IP Offices, along with dossier, classification, and citation data[1].

Common Citation Document (CCD)

The Common Citation Document (CCD) application consolidates prior art cited by all participating offices for the family members of a patent application. This tool is useful for visualizing the search results for the same invention produced by several offices on a single page, facilitating a more comprehensive understanding of the patent landscape[1].

Litigation and Enforcement

Patent Infringement Cases

The patent has been involved in litigation, as seen in the case of Nycomed US Inc. and Jagotec AG vs. Tolmar, Inc. This case highlights the importance of enforcing patent rights to protect the intellectual property of the inventors and assignees[2].

Economic and Research Implications

Patent Claims Research Dataset

The USPTO's Patent Claims Research Dataset provides detailed information on claims from U.S. patents, including those related to this invention. This dataset can be used to analyze trends and measurements of patent scope, offering insights into the economic impact and research directions in the field[3].

Public Access and Search Tools

USPTO Search Resources

The USPTO offers several tools for searching patents, including the Patent Public Search tool, which replaced legacy search tools like PubEast and PubWest. This tool provides enhanced access to prior art and is crucial for conducting thorough patent searches related to this invention[1].

Patent and Trademark Resource Centers (PTRCs)

Local PTRCs maintain search resources and offer training in patent search techniques, which can be beneficial for researchers and inventors looking to understand the patent landscape surrounding this invention[1].

Key Takeaways

  • Composition and Application: The patent covers compositions combining hyaluronic acid with prostaglandin-synthesis-inhibiting drugs for topical administration.
  • Scope and Claims: The patent includes independent and dependent claims that define the composition, its components, and methods of preparation.
  • Related Patents: Several related patents by the same inventors expand on the concept of using hyaluronic acid with various therapeutic agents.
  • Global Patent Family: Tools like Global Dossier and CCD help in understanding the global patent family and prior art citations.
  • Litigation: The patent has been involved in infringement cases, highlighting the importance of enforcement.
  • Research and Economic Impact: Datasets like the Patent Claims Research Dataset provide insights into patent scope and economic implications.

FAQs

What is the main invention described in United States Patent 5,792,753?

The main invention is a pharmaceutical composition that combines hyaluronic acid with prostaglandin-synthesis-inhibiting drugs for topical administration.

Who are the inventors of this patent?

The inventors are Falk et al.

What are the potential applications of this invention?

The compositions can be used to treat various skin conditions and inflammatory diseases.

How can one access related patent information globally?

Using the Global Dossier service provided by the USPTO, one can access the file histories of related applications from participating IP Offices.

What tools are available for searching patents related to this invention?

The USPTO offers tools like the Patent Public Search tool, PTRCs, and the Common Citation Document (CCD) application for searching and analyzing patents.

Sources

  1. USPTO - Search for patents: https://www.uspto.gov/patents/search
  2. Leda Dunn Wettre, Esq. Michael J. Gesualdo, Esq. ROBINSON, WETTRE & MILLER LLC: https://insight.rpxcorp.com/litigation_documents/3021039
  3. USPTO - Patent Claims Research Dataset: https://www.uspto.gov/ip-policy/economic-research/research-datasets/patent-claims-research-dataset
  4. Canadian Patents Database - Patent 2662581 Summary: https://brevets-patents.ic.gc.ca/opic-cipo/cpd/eng/patent/2662581/summary.html?wbdisable=true
  5. Unified Patents - US-5792753-A: https://portal.unifiedpatents.com/patents/patent/US-5792753-A

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Drugs Protected by US Patent 5,792,753

ApplicantTradenameGeneric NameDosageNDAApproval DateTETypeRLDRSPatent No.Patent ExpirationProductSubstanceDelist Req.Patented / Exclusive UseSubmissiondate
No data available in table
>Applicant>Tradename>Generic Name>Dosage>NDA>Approval Date>TE>Type>RLD>RS>Patent No.>Patent Expiration>Product>Substance>Delist Req.>Patented / Exclusive Use>Submissiondate
Showing 0 to 0 of 0 entries

International Family Members for US Patent 5,792,753

CountryPatent NumberEstimated ExpirationSupplementary Protection CertificateSPC CountrySPC Expiration
African Regional IP Organization (ARIPO) 175 ⤷  Try for Free
African Regional IP Organization (ARIPO) 448 ⤷  Try for Free
African Regional IP Organization (ARIPO) 475 ⤷  Try for Free
African Regional IP Organization (ARIPO) 476 ⤷  Try for Free
African Regional IP Organization (ARIPO) 618 ⤷  Try for Free
African Regional IP Organization (ARIPO) 9000206 ⤷  Try for Free
>Country>Patent Number>Estimated Expiration>Supplementary Protection Certificate>SPC Country>SPC Expiration
Showing 1 to 6 of 6 entries

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Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.