Details for Patent: 5,798,091

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Summary for Patent: 5,798,091

Title:	Stabilized gas emulsion containing phospholipid for ultrasound contrast enhancement
Abstract:	A gas emulsion forming composition comprising a dry, hollow, particulate, approximately microspherical material permeated with a gas or gas mixture, which upon dissolution in aqueous liquid forms a gas emulsion comprising a plurality of bubbles surrounded by a layer of at least a first and a second surfactant, wherein the first surfactant consists essentially of a phospholipid or mixture of phospholipids having at least one acyl chain which comprises at least 10 carbon atoms, and comprising at least about 5% w/w of total surfactant, and wherein the second surfactant may or may not be a phospholipid and is more water soluble than the first surfactant; kits for preparing such microbubbles; and methods for using such microbubbles as contrast agents.
Inventor(s):	Trevino; Leo A. (San Diego, CA), Schutt; Ernest George (San Diego, CA), Klein; David H. (Carlsbad, CA), Tarara; Thomas E. (San Diego, CA), Weers; Jeffry G. (San Diego, CA), Kabalnov; Alexey (San Diego, CA)
Assignee:	Alliance Pharmaceutical Corp. (San Diego, CA)
Application Number:	08/395,680
Patent Claim Types: see list of patent claims	Use; Compound; Composition;

Drugs Protected by US Patent 5,798,091

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