Details for Patent: 5,827,871
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Summary for Patent: 5,827,871
| Title: | Medicaments 1,2,3,4-tetrahydrocarbazoles and 5-HT.sub.1 agonist use thereof |
| Abstract: | Use of a compound of general formula (I): ##STR1## wherein R.sup.1 represents hydrogen, halogen, trifluoromethyl, nitro, hydroxy, C.sub.1-6 alkyl, C.sub.1-6 alkoxy, arylC.sub.1-6 alkoxy, --CO.sub.2 R.sup.4, --(CH.sub.2).sub.n CN, --(CH.sub.2).sub.n CONR.sup.5 R.sup.6, --(CH.sub.2).sub.n SO.sub.2 NR.sup.5 R.sup.6, C.sub.1-6 alkanoylamino(CH.sub.2).sub.n, or C.sub.1-6 alkylsulphonylamino(CH.sub.2).sub.n ; R.sup.4 represents hydrogen, C.sub.1-6 alkyl or arylC.sub.1-6 alkyl; R.sup.5 and R.sup.6 each independently represent hydrogen or C.sub.1-6 alkyl, or R.sup.5 and R.sup.6 together with the nitrogen atom to which they are attached form a ring; n represents 0, 1 or 2; and R.sup.2 and R.sup.3 each independently represent hydrogen, C.sub.1-6 alkyl or benzyl or together with the nitrogen atom to which they are attached form a pyrrolidino, piperidino or hexahydroazepino ring; or a physiologically acceptable salt thereof, in the manufacture of a medicament for the treatment of a condition where a 5-HT.sub.1 -like agonist is indicated, for example migraine. Novel compounds of formula (I), processes for preparing them and pharmaceutical compositions containing them are also described. |
| Inventor(s): | King; Francis David (Harlow, GB2), Gaster; Laramie Mary (Harlow, GB2), Kaumann; Alberto Julio (Trumpington, GB2), Young; Rodney Christopher (Hertford, GB2) |
| Assignee: | Smithkline Beecham plc (GB2) |
| Application Number: | 08/442,720 |
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Patent Claim Types: see list of patent claims | Use; Compound; Composition; |
Drugs Protected by US Patent 5,827,871
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
Foreign Priority and PCT Information for Patent: 5,827,871
| Foriegn Application Priority Data | ||
| Foreign Country | Foreign Patent Number | Foreign Patent Date |
| United Kingdom | 9113802 | Jun 26, 1991 |
International Family Members for US Patent 5,827,871
| Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
|---|---|---|---|---|---|
| European Patent Office | 0591280 | ⤷ Sign Up | SPC/GB03/014 | United Kingdom | ⤷ Sign Up |
| European Patent Office | 0591280 | ⤷ Sign Up | C00591280/01 | Switzerland | ⤷ Sign Up |
| European Patent Office | 0591280 | ⤷ Sign Up | C300103 | Netherlands | ⤷ Sign Up |
| European Patent Office | 0591280 | ⤷ Sign Up | 01C0019 | France | ⤷ Sign Up |
| European Patent Office | 0591280 | ⤷ Sign Up | 37/2002 | Austria | ⤷ Sign Up |
| >Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |
