Details for Patent: 6,004,565
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Summary for Patent: 6,004,565
Title: | Compositions and methods of using compositions with accelerated lymphocyte homing immunosuppressive properties |
Abstract: | The methods and compositions of the invention and the compounds used in the invention involve a novel immunosuppression mechanism, accelerated lymphocyte homing immunosuppression (ALH-immunosuppression). For example, the compound FTY720 specifically directs lymphocytes to the peripheral lymph nodes, mesenteric lymph nodes, and Peyer's patches. By reversibly sequestering lymphocytes in these tissues, the compounds can inhibit an immune response in a mammal. Understanding these mechanisms provides a novel immunosuppression therapy that can synergistically interact with other immunosuppressive compounds. Screening methods for identifying similar ALH-immunosuppression compounds are also described. The invention allows better treatments and therapies wherever an immunosuppression regimen is desired. |
Inventor(s): | Chiba; Kenji (Fukuoka, JP), Adachi; Kunitomo (Fukuoka, JP) |
Assignee: | Yoshitomi Pharmaceutical Industries, Ltd. (Osaka, JP) |
Application Number: | 08/933,738 |
Patent Litigation and PTAB cases: | See patent lawsuits and PTAB cases for patent 6,004,565 |
Patent Claim Types: see list of patent claims | Use; Composition; Dosage form; | More… ↓ |
Drugs Protected by US Patent 6,004,565
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>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
Foreign Priority and PCT Information for Patent: 6,004,565
Foriegn Application Priority Data | ||
Foreign Country | Foreign Patent Number | Foreign Patent Date |
Japan | 9-237273 | Sep 02, 1997 |
International Family Members for US Patent 6,004,565
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
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Japan | H1180026 | ⤷ Subscribe | |||
>Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |