Details for Patent: 6,020,358

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Summary for Patent: 6,020,358

Title:	Substituted phenethylsulfones and method of reducing TNF.alpha. levels
Abstract:	Phenethylsulfones substituted in the position .alpha. to the phenyl group with a 1-oxoisoindoline or 1,3-dioxoisoindoline group reduce the levels of TNF.alpha. in a mammal. Typical embodiments are 2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-aminoisoindoline- 1,3-dione and 2-[1-(3-cyclopentyloxy-4-methoxyphenyl)-2-methylsulfonylethyl]isoindoline- 1,3-dione.
Inventor(s):	Muller; George W. (Bridgewater, NJ), Man; Hon-Wah (Neshanic Station, NJ)
Assignee:	Celgene Corporation (Warren, NJ)
Application Number:	09/183,049
Patent Claim Types: see list of patent claims	Compound; Use; Composition;

Drugs Protected by US Patent 6,020,358

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