Details for Patent: 6,172,046
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Summary for Patent: 6,172,046
Title: | Combination therapy for eradicating detectable HCV-RNA in patients having chronic Hepatitis C infection |
Abstract: | There is disclosed a method for treating a patient having chronic hepatitis C infection to eradicate detectable HCV-RNA involving a combination therapy using a therapeutically effective amount of ribavirin and a therapeutically effective amount of interferon-alpha for a time period of from 20 up to 80 weeks. |
Inventor(s): | Albrecht; Janice K. (Winter Park, FL) |
Assignee: | Schering Corporation (Kenilworth, NJ) |
Application Number: | 08/938,033 |
Patent Claim Types: see list of patent claims | Use; |
Scope and claims summary: | Gene Expression Regulations by Self-Cleaving Ribozymes and Uses Thereof United States Patent 6,172,046, filed by researchers at the University of Maine in 1999, is concerned with gene expression regulation using self-cleaving ribozymes as a tool for biotechnological applications. The patent covers innovative uses of these ribozymes in modulating gene expression. Key points:
Potential impact and challenges: This gene regulation system using self-cleaving ribozymes provides new therapeutic approaches for treating diseases. Challenges may include limitations in transcriptional specificity and degradation kinetics that may lead to off-target effects. Developments following the patent: This gene regulation technology is gaining significant attention in basic research, and since its creation, there have been advancements in the field of ribozyme-mediated gene therapy and the discovery of more specific self-cleaving ribozyme tools. The impact of this patent extends beyond its initial claimed uses, focusing the community's research efforts toward a broader understanding of mammalian and recombinant gene expression systems and the novel therapeutic applications of these discovery technologies. |
Drugs Protected by US Patent 6,172,046
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International Family Members for US Patent 6,172,046
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