Details for Patent: 6,225,474
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Summary for Patent: 6,225,474
Title: | Polymorphs of 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid and method of producing the same |
Abstract: | The present invention provides a technique of selectively producing a desired polymorph of 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid. The present invention also provides a method of producing various polymorphs of 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid, which comprises crystallizing under the conditions defined by a specific temperature and a composition of a mixed solvent of methanol and water, and polymorphs obtained by the method. The present invention further provides a method of producing the other polymorphs or amorphous compounds by drying a specific polymorph under a reduced pressure with heating, and the other polymorphs or amorphous compounds obtained by the method. |
Inventor(s): | Matsumoto; Koichi (Iwakuni, JP), Watanabe; Kenzo (Iwakuni, JP), Hiramatsu; Toshiyuki (Iwakuni, JP), Kitamura; Mitsutaka (Higashi-Hiroshima, JP) |
Assignee: | Teijin Limited (Osaka, JP) |
Application Number: | 09/485,861 |
Patent Litigation and PTAB cases: | See patent lawsuits and PTAB cases for patent 6,225,474 |
Patent Claim Types: see list of patent claims | Compound; Composition; Use; |
Drugs Protected by US Patent 6,225,474
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
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>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
Foreign Priority and PCT Information for Patent: 6,225,474
Foriegn Application Priority Data | ||
Foreign Country | Foreign Patent Number | Foreign Patent Date |
Japan | 10-173079 | Jun 19, 1998 |
PCT Information | |||
PCT Filed | June 18, 1999 | PCT Application Number: | PCT/JP99/03258 |
PCT Publication Date: | December 23, 1999 | PCT Publication Number: | WO99/65885 |
International Family Members for US Patent 6,225,474
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
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European Patent Office | 1020454 | ⤷ Sign Up | PA2010005 | Lithuania | ⤷ Sign Up |
European Patent Office | 1020454 | ⤷ Sign Up | C300447 | Netherlands | ⤷ Sign Up |
European Patent Office | 1020454 | ⤷ Sign Up | CA 2010 00015 | Denmark | ⤷ Sign Up |
European Patent Office | 1020454 | ⤷ Sign Up | 91682 | Luxembourg | ⤷ Sign Up |
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