Details for Patent: 6,238,695
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Summary for Patent: 6,238,695
Title: | Formulation of fast-dissolving efavirenz capsules or tablets using super-disintegrants |
Abstract: | The present invention provides improved oral dosage form formulations of efavirenz that are useful in the inhibition of human immunodeficiency virus (HIV), the prevention or treatment of infection by HIV, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS). In particular, the present invention relates to compressed tablets or capsules comprising efavirenz that contain one or more disintegrants that enhance the dissolution rate of the efavirenz in the gastrointestinal tract thereby improving the rate and extent of absorption of efavirenz in the body. The present invention also relates to the process of making such tablets or capsules. |
Inventor(s): | Makooi-Morehead; William T. (Wallingford, PA), Buehler; John D. (Ambler, PA), Landmann; Brian R. (Hoboken, NJ) |
Assignee: | DuPont Pharmaceuticals Company (Wilmington, DE) |
Application Number: | 09/286,902 |
Patent Claim Types: see list of patent claims | Dosage form; Formulation; Process; Composition; Use; |
Drugs Protected by US Patent 6,238,695
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>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
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