Details for Patent: 6,383,471
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Summary for Patent: 6,383,471
Title: | Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents |
Abstract: | The present invention is directed to a pharmaceutical composition including a hydrophobic therapeutic agent having at least one ionizable functional group, and a carrier. The carrier includes an ionizing agent capable of ionizing the functional group, a surfactant, and optionally solubilizers, triglycerides, and neutralizing agents. The invention further relates to a method of preparing such compositions by providing a composition of an ionizable hydrophobic therapeutic agent, an ionizing agent, and a surfactant, and neutralizing a portion of the ionizing agent with a neutralizing agent. The compositions of the invention are particularly suitable for use in oral dosage forms. |
Inventor(s): | Chen; Feng-Jing (Salt Lake City, UT), Patel; Mahesh V. (Salt Lake City, UT) |
Assignee: | Lipocine, Inc. (Salt Lake City, UT) |
Application Number: | 09/287,043 |
Patent Litigation and PTAB cases: | See patent lawsuits and PTAB cases for patent 6,383,471 |
Patent Claim Types: see list of patent claims | Composition; Formulation; Dosage form; Delivery; Compound; Use; | More… ↓ |
Drugs Protected by US Patent 6,383,471
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
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>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
International Family Members for US Patent 6,383,471
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
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Australia | 3763700 | ⤷ Subscribe | |||
Canada | 2366702 | ⤷ Subscribe | |||
European Patent Office | 1165048 | ⤷ Subscribe | |||
World Intellectual Property Organization (WIPO) | 0059475 | ⤷ Subscribe | |||
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