Details for Patent: 6,667,061
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Summary for Patent: 6,667,061
Title: | Preparation of injectable suspensions having improved injectability |
Abstract: | Injectable compositions having improved injectability. The injectable compositions include microparticles suspended in an aqueous injection vehicle having a viscosity of at least 20 cp at 20.degree. C. The increased viscosity of the injection vehicle that constitutes the fluid phase of the suspension significantly reduces in vivo injectability failures. The injectable compositions can be made by mixing dry microparticles with an aqueous injection vehicle to form a suspension, and then mixing the suspension with a viscosity enhancing agent to increase the viscosity of the fluid phase of the suspension to the desired level for improved injectability. |
Inventor(s): | Ramstack; J. Michael (Lebanon, OH), Riley; M. Gary I. (Cambridge, MA), Zale; Stephen E. (Hopkinton, MA), Hotz; Joyce M. (Cincinnati, OH), Johnson; Olufunmi L. (Cambridge, MA) |
Assignee: | Alkermes Controlled Therapeutics, Inc. (Cambridge, MA) |
Application Number: | 10/259,949 |
Patent Litigation and PTAB cases: | See patent lawsuits and PTAB cases for patent 6,667,061 |
Patent Claim Types: see list of patent claims | Composition; |
Drugs Protected by US Patent 6,667,061
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