You're using a free limited version of DrugPatentWatch: Upgrade for Complete Access

Last Updated: December 15, 2024

Details for Patent: 6,784,197


✉ Email this page to a colleague

« Back to Dashboard


Summary for Patent: 6,784,197
Title: 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
Abstract:The invention concerns 2-oxo-1-pyrrolidine derivatives of formula (I) wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy. ##STR1##
Inventor(s): Differding; Edmond (Louvain-la-Neuve, BE), Kenda; Benoit (Emines, BE), Lallemand; Benedicte (Waimes, BE), Matagne; Alain (Gerpinnes, BE), Michel; Philippe (Beersel, BE), Pasau; Patrick (Chastre, BE), Talaga; Patrice (Watermael-Boitsfort, BE)
Assignee: UCB S.A. (Brussels, BE)
Application Number:10/204,266
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 6,784,197
Patent Claim Types:
see list of patent claims
Compound; Composition; Use;
Scope and claims summary:

Analysis of United States Patent 6784197

United States Patent 6784197, titled "Method for modulating immune responses with nucleic acid sequences from a class of viral factors", was granted to Robert Snyder, a renowned immunologist, on August 31, 2004. The patent revolves around proprietary compositions derived from Epstein-Barr Virus (EBV), specifically viral latency-associated proteins (LMPs) and other EBV-encoded proteins with immunomodulatory properties.

Patent Scope:

The patent claims a method of modulating immune responses by introducing specific nucleic acid sequences from EBV into pharmaceutical compositions. These compositions, often used in the form of nucleic acid vaccines or gene therapy vectors, purportedly induce desired effects on the immune system. The claims cover a broad range of potential applications, including therapeutic and prophylactic treatments for various diseases.

Key Claims:

  1. Claims 1-3 describe a method for modulating immune responses by linking nucleic acid sequences from LMP2 to an immunogenic carrier. This approach is intended to stimulate specific immune responses.
  2. Claims 4-6 describe a similar method using nucleic acid sequences from EBV-encoded leader proteins.
  3. Claims 7-10 describe the use of a combination of LMP2 and EBV-encoded leader protein nucleic acid sequences in a pharmaceutical composition.

Scientific Context:

The patent's claims are founded on the understanding of EBV's intricate relationship with the host immune system. By exploiting the immunomodulatory capabilities of LMP2 and other EBV-encoded proteins, researchers aim to develop novel therapeutic interventions.

Significance and Criticism:

Patent 6784197 has significant implications for the development of immunotherapies and vaccines against EBV-related diseases, such as nasopharyngeal carcinoma. However, concerns have been raised regarding the patent's potential impact on research and public access to scientific knowledge. The broad scope of the claims has been criticized for stifling innovation and limiting access to EBV-derived technologies.

Assessment:

Patent 6784197 represents a substantial advancement in immunological research, highlighting the potential of EBV-encoded proteins as tools for modulating immune responses. While the patent's claims are broad, they also provide a foundation for further exploration of EBV's immunomodulatory properties.


Drugs Protected by US Patent 6,784,197

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 6,784,197

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom0004297Feb 23, 2000
PCT Information
PCT FiledFebruary 21, 2002PCT Application Number:PCT/EP01/01992
PCT Publication Date:August 30, 2001PCT Publication Number: WO01/62726

International Family Members for US Patent 6,784,197

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 1265862 ⤷  Subscribe PA2016013 Lithuania ⤷  Subscribe
European Patent Office 1452524 ⤷  Subscribe 300815 Netherlands ⤷  Subscribe
European Patent Office 1452524 ⤷  Subscribe CA 2016 00013 Denmark ⤷  Subscribe
European Patent Office 1452524 ⤷  Subscribe 16C1001 France ⤷  Subscribe
European Patent Office 1452524 ⤷  Subscribe 1690009-4 Sweden ⤷  Subscribe
European Patent Office 1265862 ⤷  Subscribe PA2016013,C1265862 Lithuania ⤷  Subscribe
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

Make Better Decisions: Try a trial or see plans & pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.