Details for Patent: 6,824,822
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Summary for Patent: 6,824,822
| Title: | Residual solvent extraction method and microparticles produced thereby |
| Abstract: | Methods for preparing microparticles having reduced residual solvent levels. Microparticles are contacted with a non-aqueous washing system to reduce the level of residual solvent in the microparticles. Preferred non-aqueous washing systems include 100% ethanol and a blend of ethanol and heptane. A solvent blend of a hardening solvent and a washing solvent can be used to harden and wash microparticles in a single step, thereby eliminating the need for a post-hardening wash step. |
| Inventor(s): | Rickey; Michael E. (Loveland, OH), Ramstack; J. Michael (Lebanon, OH), Kumar; Rajesh (Loveland, OH) |
| Assignee: | Alkermes Controlled Therapeutics Inc. II (Cambridge, MA) |
| Application Number: | 09/942,631 |
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Patent Claim Types: see list of patent claims | Process; Use; |
Drugs Protected by US Patent 6,824,822
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