Details for Patent: 6,921,528

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Summary for Patent: 6,921,528

Title:	Highly efficient delivery of a large therapeutic mass aerosol
Abstract:	A method for delivering a therapeutic dose of a bioactive agent to the pulmonary system, in a single, breath-activated step, comprises administering from a receptacle enclosing a mass of particles, to a subject's respiratory tract, particles which have a tap density of less than 0.4 g/cm.sup.3 and deliver at least about 50% of the mass of particles. Another method of delivering a therapeutic dose of a bioactive agent to the pulmonary system, in a single breath, includes administering from a receptacle enclosing a mass of particles, to a subject's respiratory tract, particles which have a tap density of at least 0.4 g/cm.sup.3 and deliver at least about 10 milligrams of the bioactive agent. The receptacle can have a volume of at least 0.37 cm.sup.3.
Inventor(s):	Edwards; David A. (Boston, MA), Batvcky; Richard P. (Auburndale, MA), Johnston; Lloyd (Belmont, MA)
Assignee:	Advanced Inhalation Research, Inc. (Cambridge, MA)
Application Number:	10/681,416
Patent Claim Types: see list of patent claims	Use; Delivery;

Drugs Protected by US Patent 6,921,528

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