Details for Patent: 6,960,564
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Summary for Patent: 6,960,564
Title: | Echinocandin pharmaceutical formulations containing micelle-forming surfactants |
Abstract: | Pharmaceutical formulations are described comprising an echinocandin compound or echinocandin/carbohydrate complex and a pharmaceutically acceptable micelle-forming surfactant in a non-toxic aqueous solvent such that the solubilization of the echinocandin compound is optimized and the ability to freeze-dry the solution is maintained. Both the solution and freeze-dried formulations have increased stability. A bulking agent, tonicity agent buffer and/or a stabilizing agent may optionally be added to the formulations to further enhance the stability of the formulation. |
Inventor(s): | Milton; Nathaniel (Indianapolis, IN), Moder; Kenneth Philip (West Lafayette, IN), Sabatowski; James Lawrence (Holland, MI), Sweetana; Stephanie Ann (Bloomington, IN) |
Assignee: | Eli Lilly and Company (Indianapolis, IN) |
Application Number: | 09/942,431 |
Patent Claim Types: see list of patent claims | Formulation; Compound; Process; Use; |
Drugs Protected by US Patent 6,960,564
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