Details for Patent: 7,015,315
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Summary for Patent: 7,015,315
| Title: | Gapped oligonucleotides |
| Abstract: | Oligonucleotides and other macromolecules are provided which have increased nuclease resistance, substituent groups for increasing binding affinity to complementary strand, and subsequences of 2'-deoxy-erythro-pentofuranosyl nucleotides that activate RNase H. Such oligonucleotides and macromolecules are useful for diagnostics and other research purposes, for modulating the expression of a protein in organisms, and for the diagnosis, detection and treatment of other conditions susceptible to oligonucleotide therapeutics. |
| Inventor(s): | Cook; Phillip Dan (Vista, CA), Monia; Brett P. (Carlsbad, CA) |
| Assignee: | ISIS Pharmaceuticals, Inc. (Carlsbad, CA) |
| Application Number: | 08/465,866 |
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Patent Claim Types: see list of patent claims | Compound; |
Drugs Protected by US Patent 7,015,315
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| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
