Details for Patent: 7,108,866
✉ Email this page to a colleague
Summary for Patent: 7,108,866
Title: | Chronotherapeutic diltiazem formulations and the administration thereof |
Abstract: | A controlled-release Galenical preparation of pharmaceutically acceptable Diltiazem including the pharmaceutically acceptable salts thereof, suitable for evening dosing every 24 hours containing from about 120 mg to about 540 mg or more (as desired) of the form of Diltiazem associated with excipients to provide controlled (sustained) release of the form of Diltiazem for providing a C.sub.max of Diltiazem in the blood at between about 10 hours and about 15 hours after administration, the preparation comprising the form of Diltiazem in oral sustained-release dosage form in which the Diltiazem is adapted to be released after administration over a prolonged period of time and exhibits when given to humans(i) a higher bioavailability when given at night compared to when given in the morning without food according to FDA guidelines or criteria and(ii) bioequivalence when given in the morning with and without food according to the same FDA guidelines or criteria. |
Inventor(s): | Albert; Kenneth Stephen (Mt. Kisco, NY), Maes; Paul Jose (Oakville, CA) |
Assignee: | Biovall Laboratories International SRL (St. Michael, BB) |
Application Number: | 09/567,451 |
Patent Claim Types: see list of patent claims | Use; Composition; Dosage form; Formulation; |
Drugs Protected by US Patent 7,108,866
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
Foreign Priority and PCT Information for Patent: 7,108,866
International Family Members for US Patent 7,108,866
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
---|---|---|---|---|---|
Austria | 430561 | ⤷ Sign Up | |||
Australia | 4903700 | ⤷ Sign Up | |||
Canada | 2292247 | ⤷ Sign Up | |||
Canada | 2307547 | ⤷ Sign Up | |||
Canada | 2566590 | ⤷ Sign Up | |||
Germany | 60042168 | ⤷ Sign Up | |||
European Patent Office | 1235562 | ⤷ Sign Up | |||
>Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |