Details for Patent: 7,253,185

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Summary for Patent: 7,253,185

Title:	Amino ceramide-like compounds and therapeutic methods of use
Abstract:	The present invention provides amino ceramide-like compounds which inhibit glucosyl ceramide (GlyCer) formation by inhibiting the enzyme GlyCer synthase, thereby lowering the level of glycosphingolipids. The compounds of the present invention have improved GlcCer synthase inhibition activity and are therefore useful in therapeutic methods for treating various conditions and diseases associated with altered glycosphingolipid levels.
Inventor(s):	Shayman; James A. (Ann Arbor, MI), Harris; David J. (Lexington, MA), Siegel; Craig (Woburn, MA), Nelson; Carol A. (Westford, MA), Copeland; Diane P. (North Billerica, MA)
Assignee:	The Regents of the University of Michigan (Ann Arbor, MI) Genzyme Corporation (Cambridge, MA)
Application Number:	11/119,541
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent 7,253,185
Patent Claim Types: see list of patent claims	Composition; Compound;

Drugs Protected by US Patent 7,253,185

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