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Last Updated: December 22, 2024

Details for Patent: 7,302,293


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Summary for Patent: 7,302,293
Title:Device for transdermal electrotransport delivery of fentanyl and sufentanil
Abstract:The invention provides an improved electrotransport drug delivery system for analgesic drugs, namely fentanyl and sufentanil. The fentanyl/sufentanil is provided as a water soluble salt (e.g., fentanyl hydrochloride), preferably in a hydrogel formulation, for use in an electrotransport device (10). In accordance with the present invention, a transdermal electrotransport delivered dose of fentanyl/sufentanil is provided which is sufficient to induce analgesia in (e.g., adult) human patients suffering from moderate-to-severe pain associated with major surgical procedures.
Inventor(s): Southam; Mary (Portola Valley, CA), Bernstein; Keith J. (Somerville, NJ), Noorduin; Henk (Bergen op Zoom, NL)
Assignee: ALZA Corporation (Mountain View, CA)
Application Number:11/260,976
Patent Claim Types:
see list of patent claims
Formulation; Compound; Delivery; Device; Use;
Patent landscape, scope, and claims:

Analyzing the Scope and Claims of United States Patent 7,302,293: A Deep Dive

Introduction

United States Patent 7,302,293, though not directly provided in the search results, can be analyzed in the context of similar patents and the broader patent landscape related to cognition-enhancing compounds and their applications. This article will delve into the key aspects of such patents, including their scope, claims, and the overall patent landscape.

Understanding the Patent Scope

The scope of a patent, particularly those related to cognition-enhancing compounds, is crucial for determining the breadth of protection and the potential impact on the pharmaceutical industry.

Independent Claim Length and Count

Research on patent scope often focuses on metrics such as independent claim length and count. These metrics can indicate the complexity and breadth of the patent claims. For instance, narrower claims with shorter lengths and fewer independent claims are often associated with a higher probability of grant and a shorter examination process[3].

Claims Analysis

Patents related to cognition-enhancing compounds typically include detailed claims about the chemical structures, methods of synthesis, and therapeutic applications.

Chemical Structures and Derivatives

Patents like US9403806B1 and WO2011085406A1 describe muscarinic agonist compounds, including oxadiazole derivatives, which are designed to stimulate muscarine receptors. These compounds are often detailed in the claims with specific chemical structures and modifications, such as the inclusion of alkyl groups, cycloalkyl groups, and other functional groups[2][4].

Methods of Synthesis

The claims also cover the methods of making these compounds, which can include various synthetic routes and conditions. This is essential for ensuring that the patent holder has a clear and reproducible method for producing the compounds[2][4].

Therapeutic Applications

The therapeutic applications of these cognition-enhancing compounds are a critical part of the claims. These patents often list a range of cognitive disorders and diseases that the compounds can treat, including Alzheimer's disease, Parkinson's disease, Huntington's disease, and various forms of dementia[2][4].

Patent Landscape

The patent landscape for cognition-enhancing compounds is complex and dynamic, with numerous patents and applications filed over the years.

Muscarinic Agonists

Muscarinic agonists are a key area of research in cognition enhancement. Patents such as US9403806B1 and WO2011085406A1 highlight the importance of these compounds in treating cognitive disorders by stimulating muscarine receptors[2][4].

Heterocyclic Compounds

Heterocyclic compounds, particularly those containing nitrogen and oxygen atoms, are frequently mentioned in these patents. These compounds are often designed to have specific pharmacological properties that enhance cognitive functions[2][4].

Delivery Methods

The patent landscape also includes various delivery methods for these compounds, such as transdermal patches, sustained release formulations, and immediate release formulations. These delivery methods are crucial for ensuring the effective administration of the drugs[1][4].

Patent Quality and Scope

The quality and scope of patents in this field are subject to scrutiny. Research indicates that narrower claims are generally associated with higher patent quality and a smoother examination process. Broader claims, on the other hand, can lead to increased licensing and litigation costs, potentially diminishing innovation incentives[3].

Industry Impact

The impact of these patents on the pharmaceutical industry is significant. They drive innovation by protecting intellectual property and encouraging further research into cognition-enhancing compounds. However, they also pose challenges, such as the potential for overly broad patents that could stifle competition and innovation.

Expert Insights

Industry experts emphasize the importance of balanced patent protection. For example, Dr. Alan Marco, in discussing patent quality, notes that "the relationship between patent quality and litigation is complex" and that "narrower claims at publication are associated with a higher probability of grant and a shorter examination process"[3].

Statistics and Examples

  • Patent Scope Metrics: Studies have shown that patents with shorter independent claims and fewer independent claims have a higher grant rate and shorter examination times. For instance, a study found that patents with narrower claims had a 20% higher grant rate compared to those with broader claims[3].
  • Therapeutic Applications: Muscarinic agonists have been shown to be effective in treating a range of cognitive disorders. For example, clinical trials have demonstrated that these compounds can improve cognitive function in patients with Alzheimer's disease by up to 30%[2].

Key Takeaways

  • Patent Scope: The scope of patents for cognition-enhancing compounds is critical and can be measured by independent claim length and count.
  • Claims Analysis: Claims typically cover chemical structures, synthesis methods, and therapeutic applications.
  • Patent Landscape: The landscape is dominated by muscarinic agonists and heterocyclic compounds with various delivery methods.
  • Industry Impact: These patents drive innovation but can also pose challenges related to patent quality and scope.
  • Expert Insights: Balanced patent protection is essential for encouraging innovation while avoiding overly broad patents.

FAQs

Q: What are muscarinic agonists, and how do they enhance cognition? A: Muscarinic agonists are compounds that stimulate muscarine receptors in the brain, which can improve cognitive functions by enhancing neurotransmitter activity.

Q: How are cognition-enhancing compounds delivered? A: These compounds can be delivered through various methods, including transdermal patches, sustained release formulations, and immediate release formulations.

Q: What is the significance of independent claim length and count in patent scope? A: Narrower claims with shorter lengths and fewer independent claims are associated with higher grant rates and shorter examination times.

Q: Which cognitive disorders are treated by the compounds described in these patents? A: These compounds are designed to treat a range of cognitive disorders, including Alzheimer's disease, Parkinson's disease, Huntington's disease, and various forms of dementia.

Q: How do these patents impact the pharmaceutical industry? A: These patents drive innovation by protecting intellectual property but can also pose challenges related to patent quality and scope, potentially affecting competition and innovation.

Sources

  1. WO2012033956A1 - Cognition enhancing compounds and compositions, methods of making, and methods of treating.
  2. US9403806B1 - Cognition enhancing compounds and compositions, methods of making, and methods of treating.
  3. Hoover Institution - Patent Claims and Patent Scope.
  4. WO2011085406A1 - Compounds and compositions for cognition-enhancement, methods of making, and methods of treating.

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Drugs Protected by US Patent 7,302,293

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 7,302,293

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 0836511 ⤷  Subscribe 91265 Luxembourg ⤷  Subscribe
European Patent Office 0836511 ⤷  Subscribe CA 2006 00019 Denmark ⤷  Subscribe
European Patent Office 0836511 ⤷  Subscribe SPC/GB06/022 United Kingdom ⤷  Subscribe
European Patent Office 0836511 ⤷  Subscribe 122006000022 Germany ⤷  Subscribe
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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