Details for Patent: 7,342,005
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Summary for Patent: 7,342,005
| Title: | Antibiotic compounds |
| Abstract: | The present invention relates to carbapenems and provides a compound of the formula (I): ##STR00001## or a pharmaceutically acceptable salt or in vivo hydrolysable ester thereof wherein: R.sup.1 is 1-hydroxyethyl, 1-fluoroethyl or hydroxymethyl; R.sup.2 is hydrogen or C.sub.1-4alkyl; R.sup.3 is hydrogen or C.sub.1-4alkyl; R.sup.4 and R.sup.5 are the same or different and are selected from hydrogen, halo, cyano, C.sub.1-4alkyl, nitro, hydroxy, carboxy, C.sub.1-4alkoxy, C.sub.1-4alkoxycarbonyl, aminosulphonyl, C.sub.1-4alkylaminosulphonyl, di-C.sub.1-4-alkylaminosulphonyl, carbamoyl, C.sub.1-4alkylcarbamoyl, di-C.sub.1-4alkylcarbamoyl, trifluoromethyl, sulphonic acid, amino, C.sub.1-4alkylamino, di-C.sub.1-4alkylamino, C.sub.1-4alkanoylamino, C.sub.1-4alkanoyl(N--C.sub.1-4alkyl)amino, C.sub.1-4alkanesulphonamido and C.sub.1-4alkylS(O).sub.n--wherein n is zero, one or two; with the proviso that there is no hydroxy or carboxy substituent in a position ortho to the link to --NR.sup.3--; processes for their preparation, intermediates in their preparation, their use as therapeutic agents and pharmaceutical compositions containing them. |
| Inventor(s): | Betts; Michael John (Wilmslow, GB), Davies; Gareth Morse (Macclesfield, GB), Swain; Michael Lingard (Stockport, GB) |
| Assignee: | AstraZeneca UK Limited (London, GB) |
| Application Number: | 11/126,331 |
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Patent Claim Types: see list of patent claims | Composition; Formulation; Compound; Process; |
Drugs Protected by US Patent 7,342,005
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
Foreign Priority and PCT Information for Patent: 7,342,005
| Foriegn Application Priority Data | ||
| Foreign Country | Foreign Patent Number | Foreign Patent Date |
| United Kingdom | 9202298.7 | Feb 04, 1992 |
International Family Members for US Patent 7,342,005
| Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
|---|---|---|---|---|---|
| European Patent Office | 0579826 | ⤷ Sign Up | SPC027/2002 | Ireland | ⤷ Sign Up |
| European Patent Office | 0579826 | ⤷ Sign Up | CA 2002 00025 | Denmark | ⤷ Sign Up |
| European Patent Office | 0579826 | ⤷ Sign Up | C00579826/01 | Switzerland | ⤷ Sign Up |
| European Patent Office | 0579826 | ⤷ Sign Up | SPC/GB02/042 | United Kingdom | ⤷ Sign Up |
| European Patent Office | 0579826 | ⤷ Sign Up | C300104 | Netherlands | ⤷ Sign Up |
| European Patent Office | 0579826 | ⤷ Sign Up | 02C0041 | France | ⤷ Sign Up |
| >Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |
