Details for Patent: 7,348,361
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Summary for Patent: 7,348,361
Title: | Solution for diagnosing or treating tissue pathologies |
Abstract: | The invention concerns a 5-aminolevulinic acid ester (E-ALA) solution for producing a pharmaceutical preparation useful for diagnosing and/or treating tissue and/or cell pathologies by local radiation exposure using radiation emitted by a light source energy followed, in the case diagnosis, by detection of fluorescent protoporphyrin IX (Pp1X). The E-ALA concentration in the solution is less than 1% and ranges between 0.01% and 0.5%. The low E-ALA concentration in the solution increases Pp1X synthesis and homogenises its distribution in the cell layers while highly reducing the secondary toxicity for the treated cells. |
Inventor(s): | Marti; Alexandre (Geneva, CH), Lange; Norbert (Lausanne, CH), Zellweger; Matthieu (Lausanne, CH), Wagnieres; Georges (Morges, CH), Van Den Bergh; Hubert (Goumoens-la-Ville, CH), Jichlinski; Patrice (Le Mont-sur-Lausanne, CH), Kucera; Pavel (Lausanne, CH) |
Assignee: | Ecole Polytechnique Federale de Lausanne (Lausanne, CH) |
Application Number: | 09/673,871 |
Patent Claim Types: see list of patent claims | Use; Composition; Compound; Formulation; |
Drugs Protected by US Patent 7,348,361
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
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>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
Foreign Priority and PCT Information for Patent: 7,348,361
Foriegn Application Priority Data | ||
Foreign Country | Foreign Patent Number | Foreign Patent Date |
France | 98 05425 | Apr 22, 1998 |
PCT Information | |||
PCT Filed | April 22, 1999 | PCT Application Number: | PCT/CH99/00163 |
PCT Publication Date: | October 28, 1999 | PCT Publication Number: | WO99/53962 |
International Family Members for US Patent 7,348,361
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
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Austria | 228018 | ⤷ Sign Up | |||
Canada | 2327393 | ⤷ Sign Up | |||
Germany | 69904033 | ⤷ Sign Up | |||
European Patent Office | 1073472 | ⤷ Sign Up | |||
Spain | 2188146 | ⤷ Sign Up | |||
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