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Last Updated: November 24, 2024

Details for Patent: 7,348,361


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Summary for Patent: 7,348,361
Title:Solution for diagnosing or treating tissue pathologies
Abstract:The invention concerns a 5-aminolevulinic acid ester (E-ALA) solution for producing a pharmaceutical preparation useful for diagnosing and/or treating tissue and/or cell pathologies by local radiation exposure using radiation emitted by a light source energy followed, in the case diagnosis, by detection of fluorescent protoporphyrin IX (Pp1X). The E-ALA concentration in the solution is less than 1% and ranges between 0.01% and 0.5%. The low E-ALA concentration in the solution increases Pp1X synthesis and homogenises its distribution in the cell layers while highly reducing the secondary toxicity for the treated cells.
Inventor(s): Marti; Alexandre (Geneva, CH), Lange; Norbert (Lausanne, CH), Zellweger; Matthieu (Lausanne, CH), Wagnieres; Georges (Morges, CH), Van Den Bergh; Hubert (Goumoens-la-Ville, CH), Jichlinski; Patrice (Le Mont-sur-Lausanne, CH), Kucera; Pavel (Lausanne, CH)
Assignee: Ecole Polytechnique Federale de Lausanne (Lausanne, CH)
Application Number:09/673,871
Patent Claim Types:
see list of patent claims
Use; Composition; Compound; Formulation;

Drugs Protected by US Patent 7,348,361

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 7,348,361

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
France98 05425Apr 22, 1998
PCT Information
PCT FiledApril 22, 1999PCT Application Number:PCT/CH99/00163
PCT Publication Date:October 28, 1999PCT Publication Number: WO99/53962

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