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Last Updated: November 23, 2024

Details for Patent: 7,435,745


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Summary for Patent: 7,435,745
Title:Methods and compositions for inhibition of angiogenesis
Abstract:The present invention comprises a group of compounds that effectively inhibit angiogenesis. More specifically, thalidomide and various related compounds such as thalidomide precursors, analogs, metabolites and hydrolysis products have been shown to inhibit angiogenesis and to treat disease states resulting from angiogenesis. Additionally, antiinflammatory drugs, such as steroids and NSAIDs can inhibit angiogenesis dependent diseases either alone or in combination with thalidomide and related compounds. Importantly, these compounds can be administered orally.
Inventor(s): D'Amato; Robert J. (Cambridge, MA)
Assignee: Celgene Corporation (Summit, NJ)
Application Number:11/411,230
Patent Claim Types:
see list of patent claims
Use; Delivery;

Drugs Protected by US Patent 7,435,745

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
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