Details for Patent: 7,592,339

Summary for Patent: 7,592,339

Title:	Substituted oxazolidinones and their use in the field of blood coagulation
Abstract:	The invention relates to the field of blood coagulation. Novel oxazolidinone derivatives of the general formula (I) ##STR00001## processes for their preparation and their use as medicinally active compounds for the prophylaxis and/or treatment of disorders are described.
Inventor(s):	Straub; Alexander (Wuppertal, DE), Lampe; Thomas (Wuppertal, DE), Pohlmann; Jens (Wuppertal, DE), Rohrig; Susanne (Essen, DE), Perzborn; Elisabeth (Wuppertal, DE), Schlemmer; Karl-Heinz (Wuppertal, DE), Pernerstorfer; Joseph (Wuppertal, DE)
Assignee:	Bayer Schering Pharma Aktiengesellschaft (Berlin, DE)
Application Number:	11/460,529
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent 7,592,339
Patent Claim Types: see list of patent claims	Use;

Analyzing the Scope and Claims of United States Patent 7,592,339

Introduction

United States Patent 7,592,339, titled "Substituted oxazolidinones and their use in the field of blood coagulation," is a patent that has significant implications in the pharmaceutical industry, particularly in the area of blood coagulation. This analysis will delve into the scope, claims, and the broader patent landscape surrounding this invention.

Patent Overview

The patent, filed as US11/460,529, was granted on September 22, 2009, and has since expired due to fee-related issues[4].

Invention Description

The invention pertains to novel oxazolidinone derivatives and their processes for preparation. These compounds are designed for use in the field of blood coagulation, which is crucial for treating and preventing conditions such as thrombosis and other cardiovascular diseases[4].

Claim Structure

The patent includes multiple claims that define the scope of the invention. Here are some key aspects of the claim structure:

Independent Claims

Independent claims are those that stand alone and do not depend on other claims. In this patent, the independent claims typically describe the novel oxazolidinone derivatives, their chemical structures, and the processes for their preparation. For example, Claim 1 might describe a specific oxazolidinone derivative with a particular chemical formula and its use in blood coagulation[4].

Dependent Claims

Dependent claims build upon the independent claims and provide additional details or limitations. These claims might specify particular substituents, methods of synthesis, or specific applications within the field of blood coagulation. Dependent claims help to narrow the scope of the invention and provide a clearer definition of what is protected[4].

Scope of the Patent

The scope of a patent is determined by its claims, and in this case, the claims are focused on the specific chemical compounds and their uses.

Chemical Compounds

The patent protects a range of oxazolidinone derivatives, each with specific structural features. These compounds are designed to interact with biological systems involved in blood coagulation, making them potential therapeutic agents[4].

Processes for Preparation

The patent also covers the methods for synthesizing these oxazolidinone derivatives. This includes various chemical reactions and conditions necessary to produce the desired compounds. Protecting these processes ensures that the patent holder has control over how the compounds are made[4].

Patent Landscape

The patent landscape surrounding US 7,592,339 involves several key aspects:

Related Patents

There are other patents related to oxazolidinone derivatives and their use in blood coagulation. For instance, patents like WO2013151719A2 describe fluorinated oxazolidinone derivatives, which are also used in the same field. These patents collectively form a complex landscape where multiple players have intellectual property rights[5].

Patent Thickets

The concept of "patent thickets" is relevant here. Patent thickets refer to a large number of patents that cover a particular technology or product, making it difficult for new entrants to navigate without infringing on existing patents. In the pharmaceutical industry, especially with biologics and biosimilars, patent thickets can significantly delay market entry for generic or biosimilar products[1].

Litigation and Challenges

Patents in the pharmaceutical sector are often subject to litigation and challenges. For example, inter partes review (IPR) and post-grant review (PGR) proceedings at the USPTO can be costly and time-consuming, with budgets sometimes exceeding $774,000 for a single patent challenge. This environment makes patent settlements crucial for generic and biosimilar manufacturers[1].

Quality and Validity of Patents

The quality and validity of patents, including US 7,592,339, are critical issues. Research has shown that the scope of patent claims can impact their validity and the overall innovation landscape. Narrower claims, which are often the result of a longer examination process, are associated with a higher probability of grant and shorter examination times. This suggests that the specificity and clarity of claims in US 7,592,339 would be important factors in determining its validity and enforceability[3].

Impact on Innovation

The patent landscape, including patents like US 7,592,339, can influence innovation in several ways:

Licensing and Litigation Costs

Overly broad or questionable patents can increase licensing and litigation costs, potentially diminishing incentives for innovation. However, well-defined and valid patents like US 7,592,339 can protect genuine innovations and encourage further research and development[3].

Access to Biosimilars

In the context of biosimilars, patents can delay market entry, affecting patient access to affordable treatments. The strategy of amassing large numbers of patents, including terminally disclaimed patents, can make it highly uncertain and cost-prohibitive for generic or biosimilar manufacturers to enter the market before the last patent expires[1].

Conclusion

United States Patent 7,592,339 is a significant patent in the field of blood coagulation, protecting novel oxazolidinone derivatives and their preparation processes. Understanding its scope, claims, and the broader patent landscape is crucial for navigating the complex world of pharmaceutical patents.

Key Takeaways

• Patent Scope: The patent protects specific oxazolidinone derivatives and their synthesis methods.
• Claim Structure: Includes independent and dependent claims that define the invention's scope.
• Patent Landscape: Part of a larger landscape involving related patents and potential patent thickets.
• Quality and Validity: Narrower claims are generally associated with higher validity and enforceability.
• Impact on Innovation: Well-defined patents can protect innovations but overly broad patents can increase costs and hinder innovation.

FAQs

1. What is the main subject of United States Patent 7,592,339?

   • The patent pertains to novel oxazolidinone derivatives and their use in the field of blood coagulation.

2. What are the key components of the claims in this patent?

   • The claims include descriptions of the chemical compounds, their specific structures, and the processes for their preparation.

3. How does the patent landscape affect generic or biosimilar manufacturers?

   • The presence of multiple patents, including terminally disclaimed patents, can make market entry highly uncertain and cost-prohibitive for generic or biosimilar manufacturers.

4. What is the impact of patent scope on innovation?

   • Narrower, well-defined claims can protect genuine innovations and encourage further research, while overly broad claims can increase costs and diminish innovation incentives.

5. Why are patent settlements important in the pharmaceutical industry?

   • Patent settlements are crucial due to the high costs and complexities involved in challenging patents, especially in an environment where many patents are of questionable quality.

Sources

1. Letterhead DC Office - Regulations.gov

   • [PDF] Letterhead DC Office - Regulations.gov

2. US-7592339-B2 - Unified Patents Portal

   • US-7592339-B2 - Unified Patents Portal

3. Patent Claims and Patent Scope - SSRN

   • Patent Claims and Patent Scope - SSRN

4. US7592339B2 - Substituted oxazolidinones and their use in the field of blood coagulation - Google Patents

   • US7592339B2 - Substituted oxazolidinones and their use in the field of blood coagulation - Google Patents

5. WO2013151719A2 - Fluorinated oxazolidinone ... - Google Patents

   • WO2013151719A2 - Fluorinated oxazolidinone ... - Google Patents

Drugs Protected by US Patent 7,592,339

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
No data available in table

International Family Members for US Patent 7,592,339

Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
European Patent Office	1261606		91497	Luxembourg
European Patent Office	1261606		PA2008018	Lithuania
European Patent Office	1261606		CA 2008 00050	Denmark
European Patent Office	1261606		300370	Netherlands
European Patent Office	1261606		PA2008018,C1261606	Lithuania