Details for Patent: 7,608,280

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Summary for Patent: 7,608,280

Title:	Method of producing FR901228
Abstract:	Depsipeptides and congeners thereof are disclosed having structure (I), wherein m, n, p, q, X, R1, R2 and R3 are as defined herein. These compounds, including FR901228, have activity as, for example, immunosuppressants, as well as for the prevention or treatment of patients suffering or at risk of suffering from inflammatory, autoimmune or immune system-related diseases including graft-versus-host disease and enhancement of graft/tissue survival following transplant. Also provided are methods for inhibiting lymphocyte activation, proliferation, and/or suppression of IL-2 secretion. Also provided are crystalline forms of FR901228, e.g., type A and type B crystalline forms of FR901228.
Inventor(s):	Ueda; Satoshi (Chuo-ku, JP), Watamoto; Yoko (Chuo-ku, JP), Tsuboi; Masaru (Chuo-ku, JP), Kanda; Munekazu (Chuo-ku, JP), Higaki; Tomoji (Chuo-ku, JP), Matsuda; Mitsunori (Chuo-ku, JP)
Assignee:	Astellas Pharma Inc. (Tokyo, JP)
Application Number:	12/049,746
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent 7,608,280
Patent Claim Types: see list of patent claims	Compound; Composition;

Drugs Protected by US Patent 7,608,280

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

Foreign Priority and PCT Information for Patent: 7,608,280

Foriegn Application Priority Data
Foreign Country	Foreign Patent Number	Foreign Patent Date
Japan	2000-265414	Sep 01, 2000

International Family Members for US Patent 7,608,280

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Argentina	030714	⤷ Sign Up
Australia	8010901	⤷ Sign Up
European Patent Office	1313872	⤷ Sign Up
Japan	2004508049	⤷ Sign Up
World Intellectual Property Organization (WIPO)	0220817	⤷ Sign Up
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