Details for Patent: 7,662,365

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Summary for Patent: 7,662,365

Title:	Polymer conjugates of opioid antagonists
Abstract:	The invention provides polymer conjugates of opioid antagonists comprising a polymer, such as poly(ethylene glycol), covalently attached to an opioid antagonist. The linkage between the polymer and the opioid antagonist is preferably hydrolytically stable. The invention also includes a method of treating one or more side effects associated with the use of opioid analgesics, such as constipation, nausea, or pruritus, by administering a polymer conjugate of the invention.
Inventor(s):	Bentley; Michael David (Huntsville, AL), Roberts; Michael James (Williamsburg, VA), Shen; Xiaoming (Madison, AL), Cheng; Lin (Huntsville, AL)
Assignee:	Nektar Therapeutics (San Carlos, CA)
Application Number:	11/332,964
Patent Claim Types: see list of patent claims	Compound; Composition;

Drugs Protected by US Patent 7,662,365

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