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Last Updated: December 23, 2024

Details for Patent: 8,133,879


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Summary for Patent: 8,133,879
Title:Myocardial perfusion imaging methods and compositions
Abstract: The present disclosure provides 2-adenosine N-pyrazole compounds of structural formula shown below that are potent and selective agonists for A.sub.2A adenosine receptor, compositions comprising these compounds, and methods for using these compounds in a variety of applications including myocardial perfusion imaging methods. ##STR00001##
Inventor(s): Belardinelli; Luiz (Palo Alto, CA), Rosner; Mitchell (Mountain View, CA)
Assignee: Gilead Sciences, Inc. (Foster City, CA)
Application Number:12/749,328
Patent Claim Types:
see list of patent claims
Composition; Compound; Delivery;
Patent landscape, scope, and claims:

United States Patent 8,133,879: A Detailed Analysis of Scope, Claims, and Patent Landscape

Introduction

United States Patent 8,133,879, titled "Myocardial Perfusion Imaging Methods and Compositions," is a significant patent in the field of medical imaging, particularly focusing on myocardial perfusion imaging. This analysis will delve into the scope, claims, and the broader patent landscape surrounding this invention.

Background and Invention Overview

The patent, assigned to Gilead Sciences, Inc., is a continuation of several earlier applications, including those filed in 2003 and 2004. It relates to methods and compositions for myocardial perfusion imaging, which is crucial for diagnosing and managing cardiovascular diseases[1].

Scope of the Patent

The scope of the patent encompasses the administration of specific pharmaceutical compositions for imaging myocardial perfusion. This includes the use of certain compounds that enhance the visibility of myocardial tissue during imaging procedures. The patent's scope is defined by its claims, which specify the exact methods and compositions covered.

Claims Analysis

The patent includes multiple claims that define the invention's boundaries. These claims can be categorized into independent and dependent claims.

  • Independent Claims: These claims stand alone and define the broadest aspects of the invention. For example, Claim 1 might describe the method of administering a pharmaceutical composition for myocardial perfusion imaging.
  • Dependent Claims: These claims build upon the independent claims and provide additional details or limitations. For instance, a dependent claim might specify the dosage or the route of administration of the pharmaceutical composition[1].

Claim Language and Scope Metrics

The clarity and breadth of patent claims are critical in determining the patent's scope. Metrics such as independent claim length and independent claim count can be used to measure patent scope. Narrower claims, as indicated by shorter lengths and fewer counts, are often associated with a higher probability of grant and a shorter examination process[3].

Patent Examination Process

The examination process for this patent would have involved a thorough review by the USPTO to ensure that the claims are novel, non-obvious, and fully described. The process may have included office actions, where the examiner could have requested clarifications or amendments to the claims. The patent's history shows that it is part of a series of continuations, indicating that the inventors refined their claims over time to meet the USPTO's requirements[1].

Prior Art and Related Patents

The patent landscape for myocardial perfusion imaging includes several related patents and prior art. The patent cites numerous earlier patents and publications, such as those by Miyashita et al., Kogi et al., and Yamaguchi et al., which are relevant to the field of myocardial imaging[1].

Global Patent Landscape

The global patent landscape for medical imaging, particularly myocardial perfusion imaging, is complex and involves multiple jurisdictions. Tools like the Global Dossier and the Common Citation Document (CCD) can help in understanding the international patent family and the prior art cited by different patent offices[4].

Impact on Innovation and Litigation

The clarity and scope of patent claims can significantly impact innovation and litigation. Broad or unclear claims can lead to increased licensing and litigation costs, potentially hindering innovation. In contrast, narrower and clearer claims can facilitate a more efficient examination process and reduce the likelihood of disputes[3].

Industry Expert Insights

Industry experts often emphasize the importance of well-defined patent claims. For instance, a Federal Trade Commission (FTC) report highlighted concerns about overly broad and unclear claims in software and internet patents, which can impede innovation[3].

Statistics and Trends

Statistics show that patents with narrower claims at publication have a higher probability of grant and a shorter examination process. This trend is observed across various technology areas, including medical imaging. The examination process tends to narrow the scope of patent claims, especially when the duration of examination is longer[3].

Practical Applications and Future Directions

The methods and compositions described in this patent have practical applications in clinical settings for diagnosing and managing cardiovascular diseases. Future directions may include further refinements in imaging techniques and the development of new pharmaceutical compositions that enhance imaging outcomes.

Key Takeaways

  • The patent covers specific methods and compositions for myocardial perfusion imaging.
  • The scope is defined by independent and dependent claims.
  • Narrower claims are associated with a higher probability of grant and shorter examination process.
  • The patent is part of a broader landscape involving multiple related patents and prior art.
  • Clear and well-defined claims are crucial for innovation and reducing litigation costs.

Frequently Asked Questions (FAQs)

Q: What is the main focus of United States Patent 8,133,879?

A: The main focus is on methods and compositions for myocardial perfusion imaging.

Q: How are the claims in this patent structured?

A: The claims include independent claims that define the broad aspects of the invention and dependent claims that provide additional details.

Q: What metrics are used to measure patent scope?

A: Metrics such as independent claim length and independent claim count are used to measure patent scope.

Q: How does the examination process affect patent claims?

A: The examination process tends to narrow the scope of patent claims, especially when the duration of examination is longer.

Q: What is the significance of clear and well-defined patent claims?

A: Clear and well-defined claims are crucial for facilitating innovation and reducing litigation costs.

Cited Sources

  1. United States Patent and Trademark Office, "MYOCARDIAL PERFUSION IMAGING METHODS AND COMPOSITIONS," US Patent 8,133,879 B2, June 25, 2013.
  2. United States Patent and Trademark Office, "A method of myocardial perfusion imaging of a human in need thereof," US Patent 9,289,446 B2, November 4, 2014.
  3. Hoover Institution, "Patent Claims and Patent Scope," Working Paper Series No. 16001, August 18, 2016.
  4. United States Patent and Trademark Office, "Search for patents," October 18, 2018.

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Drugs Protected by US Patent 8,133,879

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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