Details for Patent: 8,183,226

Summary for Patent: 8,183,226

Title:	Myocardial perfusion imaging method
Abstract:	The present disclosure provides 2-adenosine N-pyrazole compounds exemplified by the structure shown below that are potent and selective agonists for A.sub.2A adenosine receptor, compositions comprising these compounds, and methods for using these compounds in a variety of applications including myocardial perfusion imaging and coronary vasodilation methods. ##STR00001##
Inventor(s):	Belardinelli; Luiz (Menlo Park, CA)
Assignee:	Gilead Sciences, Inc. (Foster City, CA)
Application Number:	12/695,096
Patent Claim Types: see list of patent claims	Use;

Understanding the Scope and Claims of United States Patent 8,183,226

Introduction to Patent 8,183,226

United States Patent 8,183,226, titled "Myocardial Perfusion Imaging Method," is a patent that deals with a specific medical imaging technique. To analyze the scope and claims of this patent, it is essential to delve into its details, the context of its issuance, and the broader patent landscape.

Patent Overview

Publication and Authority

• The patent was published on May 22, 2012, and is assigned the publication number US8183226B2. It falls under the authority of the United States Patent and Trademark Office (USPTO)[4].

Inventors and Assignees

• While the specific inventors and assignees are not detailed in the provided sources, this information can typically be found in the patent document itself. The assignee is usually the entity that owns the rights to the patent.

Prior Art and Legal Status

• The patent's prior art keywords include terms like "cvt," "alkyl," "aryl," "administered," and "substituted," indicating the chemical and pharmaceutical nature of the invention. The legal status of the patent is listed as "Expired - Fee Related," meaning it has expired due to non-payment of maintenance fees[4].

Claims of the Patent

Claim Structure

• The claims of a patent are the most critical part as they define the scope of the invention. For Patent 8,183,226, the claims would typically be divided into independent and dependent claims. Independent claims stand alone and define the invention, while dependent claims refer back to and further limit the independent claims[3].

Claim Examples

• Although the specific claims of this patent are not provided here, they would generally describe the myocardial perfusion imaging method, including the compounds used (such as 2-adenosine N-pyrazole compounds), the method of administration, and the specific steps involved in the imaging process.

Scope of the Patent

Invention Description

• The patent describes a method for myocardial perfusion imaging using specific compounds that are potent and selective agonists for A2A adenosine receptors. This method is designed to improve the imaging of myocardial perfusion, which is crucial for diagnosing and managing heart conditions[4].

Technical Details

• The technical details include the chemical structure of the compounds, their synthesis, and how they are administered. The patent would also describe the imaging protocol and any specific equipment or techniques required for the method.

Patent Landscape

Historical Context

• Patents related to medical imaging and pharmaceuticals have a long history. The USPTO has been granting patents in these fields since the early days of the patent system. For example, historical patents from 1790 to 1836, known as the "X" patents, laid the groundwork for modern patent law[1].

Current Trends

• The current patent landscape in medical imaging and pharmaceuticals is highly competitive and rapidly evolving. The USPTO's Patent Claims Research Dataset provides insights into the trends and scope of patents in these fields, including detailed information on claims and their dependency relationships[3].

Economic and Legal Implications

Patent Law and Policy

• The issuance and maintenance of patents like US8183226B2 are governed by U.S. patent law, which is designed to promote the progress of science and useful arts by securing exclusive rights to inventors for limited times. This is rooted in Article I, Section 8 of the U.S. Constitution[2].

International Aspects

• Patents can have international implications, especially if the invention is filed in multiple countries. The U.S. patent law allows foreign applicants to file for U.S. patents under certain conditions, and priority can be claimed based on earlier foreign filings[2].

Practical Applications and Impact

Medical Significance

• The myocardial perfusion imaging method described in this patent has significant medical implications. It can improve the diagnosis and treatment of heart conditions by providing clearer and more accurate images of myocardial perfusion.

Commercial Impact

• The commercial impact of such a patent can be substantial, as it can lead to the development of new medical imaging products and services. However, the expiration of the patent due to non-payment of fees means that the exclusive rights to the invention are no longer in effect.

Key Takeaways

• Patent Details: US8183226B2 is a patent for a myocardial perfusion imaging method using specific compounds.
• Claims and Scope: The patent's claims define the method and compounds used, while the scope includes the technical details and application of the method.
• Patent Landscape: The patent is part of a broader landscape of medical imaging and pharmaceutical patents, with historical and current trends influencing its significance.
• Legal and Economic Implications: Governed by U.S. patent law, the patent has implications for both domestic and international patent filings and commercial applications.

FAQs

1. What is the main invention described in US8183226B2?

   • The main invention is a method for myocardial perfusion imaging using 2-adenosine N-pyrazole compounds.

2. Why is the patent listed as expired?

   • The patent is listed as expired due to non-payment of maintenance fees.

3. Can foreign applicants file for U.S. patents?

   • Yes, foreign applicants can file for U.S. patents under certain conditions and can claim priority based on earlier foreign filings.

4. What is the significance of the USPTO's Patent Claims Research Dataset?

   • The dataset provides detailed information on claims from U.S. patents and applications, helping in understanding trends and scope in various patent fields.

5. How do historical patents influence modern patent law?

   • Historical patents, such as those from 1790 to 1836, laid the groundwork for modern patent law and continue to influence how patents are granted and maintained today.

Drugs Protected by US Patent 8,183,226

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
No data available in table

International Family Members for US Patent 8,183,226

Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Australia	2003259264
Canada	2492855
China	1671399
European Patent Office	1524984