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Last Updated: November 28, 2024

Details for Patent: 8,188,085


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Which drugs does patent 8,188,085 protect, and when does it expire?

Patent 8,188,085 protects BREXAFEMME and is included in one NDA.

This patent has nine patent family members in seven countries.

Summary for Patent: 8,188,085
Title:Antifungal agents
Abstract: Novel derivatives of enfumafungin are disclosed herein, along with their pharmaceutically acceptable salts, hydrates and prodrugs. Also disclosed are compositions comprising such compounds, methods of preparing such compounds and methods of using such compounds as antifungal agents and/or inhibitors of (1,3)-.beta.-D-glucan synthase. The disclosed compounds, their pharmaceutically acceptable salts, hydrates and prodrugs, as well as compositions comprising such compounds, salts, hydrates and prodrugs, are useful for treating and/or preventing fungal infections and associated diseases and conditions.
Inventor(s): Greenlee; Mark L. (Plainfield, NJ), Wilkening; Robert (Maplewood, NJ), Apgar; James (Edison, NJ), Sperbeck; Donald (East Hanover, NJ), Wildonger; Kenneth J. (Bridgewater, NJ), Meng; Dongfang (Westfield, NJ), Parker, Jr.; Dann L. (Cranford, NJ), Pacofsky; Gregory J. (Raleigh, NC), Heasley; Brian H. (Wake Forest, NC), Mamai; Ahmed (Raleigh, NC), Nelson; Kingsley (Mebane, NC)
Assignee: Merck Sharp & Dohme Corp. (Rahway, NC) Seynexis, Inc. (Research Triangle Park, NC)
Application Number:12/461,318
Patent Claim Types:
see list of patent claims
Use; Composition; Compound;

Drugs Protected by US Patent 8,188,085

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Scynexis BREXAFEMME ibrexafungerp citrate TABLET;ORAL 214900-001 Jun 1, 2021 RX Yes Yes ⤷  Sign Up ⤷  Sign Up Y Y TREATMENT OF ADULT AND POST-MENARCHAL PEDIATRIC FEMALES WITH VULVOVAGINAL CANDIDIASIS (VVC) ⤷  Sign Up
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 8,188,085

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2009282474 ⤷  Sign Up
Canada 2731941 ⤷  Sign Up
China 102176827 ⤷  Sign Up
China 104877001 ⤷  Sign Up
European Patent Office 2326181 ⤷  Sign Up
Hong Kong 1214271 ⤷  Sign Up
Japan 2011530593 ⤷  Sign Up
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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