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Last Updated: November 2, 2024

Details for Patent: 8,394,826


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Summary for Patent: 8,394,826
Title:Dual mechanism inhibitors for the treatment of disease
Abstract: Provided are compounds that are inhibitors of both rho kinase and of a monoamine transporter (MAT) act to improve the disease state or condition. Further provided are compositions comprising the compounds. Further provided are methods for treating diseases or conditions, the methods comprising administering compounds according to the invention. One such disease may be glaucoma for which, among other beneficial effects, a marked reduction in intraocular pressure (IOP) may be achieved.
Inventor(s): deLong; Mitchell A. (Chapel Hill, NC), Sturdivant; Jill Marie (Chapel Hill, NC), Royalty; Susan M. (Cary, NC)
Assignee: Aerie Pharmaceuticals, Inc. (Research Triangle Park, NC)
Application Number:12/694,965
Patent Claim Types:
see list of patent claims
Use; Composition; Compound;

Drugs Protected by US Patent 8,394,826

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Alcon Labs Inc RHOPRESSA netarsudil mesylate SOLUTION/DROPS;OPHTHALMIC 208254-001 Dec 18, 2017 RX Yes Yes ⤷  Sign Up ⤷  Sign Up Y Y REDUCTION OF ELEVATED INTRAOCULAR PRESSURE ⤷  Sign Up
Alcon Labs Inc ROCKLATAN latanoprost; netarsudil dimesylate SOLUTION/DROPS;OPHTHALMIC 208259-001 Mar 12, 2019 RX Yes Yes ⤷  Sign Up ⤷  Sign Up Y Y REDUCTION OF ELEVATED INTRAOCULAR PRESSURE ⤷  Sign Up
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 8,394,826

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 3053913 ⤷  Sign Up 301038 Netherlands ⤷  Sign Up
European Patent Office 3053913 ⤷  Sign Up 122020000016 Germany ⤷  Sign Up
European Patent Office 3053913 ⤷  Sign Up 2020C/510 Belgium ⤷  Sign Up
European Patent Office 3053913 ⤷  Sign Up 132020000000043 Italy ⤷  Sign Up
European Patent Office 3053913 ⤷  Sign Up 2020/016 Ireland ⤷  Sign Up
European Patent Office 3053913 ⤷  Sign Up C202030018 Spain ⤷  Sign Up
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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